Q.

What are the characteristics of the mixed monolithic-reservoir devices?

A. the drug has a large therapeutic index
B. drug permeation rate is high
C. the drug-polymer matrix is layered by rate- controlling membrane
D. administration of emulsions
Answer» C. the drug-polymer matrix is layered by rate- controlling membrane
Explanation: this device has drug release kinetics intermediate between monolithic and reservoir systems. here the drug-polymer matrix is layered by a rate controlling membrane. the release is controlled initially by the membrane but as the drug gets depleted the rate is controlled by diffusion of the drug.
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