a. The half life is the time taken for a parameter to fall to 1/4 its original value
B. Partial agonists act at receptor sites to cause maximal pharmacological effect at high doses
c. Diazepam has a high extraction ratio and is thus subject to flow dependent elimination
d. Morphine and pethidine have the same potency
e. A patient with oedema will have an increased volume of distribution of tobramycin