McqMate
Chapters
1. |
Which is a water soluble vitamin? |
A. | D |
B. | B12 |
C. | A |
D. | K |
Answer» B. B12 |
2. |
Which is not Na+ dependent for absorption? |
A. | thiamin |
B. | riboflavin |
C. | niacin |
D. | folate |
Answer» D. folate |
3. |
Which is absorbed mainly in the colon? |
A. | short chain fatty acids |
B. | calcium |
C. | vitamin K |
D. | oligosaccharides |
Answer» A. short chain fatty acids |
4. |
Which is INCORRECT regarding nerve supply to the gut? |
A. | the blood vessels are known to have enteric, parasympathetic and sympathetic innervation |
B. | the myenteric plexus lies between the longitudinal and circular muscle layers |
C. | parasympathetic supply is via vagal and sacral nerve |
D. | sympathetic supply is often inhibitory on cholinergic postganglionic fibres |
Answer» A. the blood vessels are known to have enteric, parasympathetic and sympathetic innervation |
5. |
Gastrin secretion is stimulated by all but: |
A. | luminal peptides |
B. | vagal discharge |
C. | luminal acid |
D. | phenylalanine |
Answer» C. luminal acid |
6. |
The actions of gastrin include all but: |
A. | insulin secretion in response to a carbohydrate meal |
B. | a trophic effect on colonic mucosa |
C. | a trophic effect on gastric mucosa |
D. | pepsin secretion |
Answer» A. insulin secretion in response to a carbohydrate meal |
7. |
Which is NOT an action of CCK? |
A. | gallbladder contraction |
B. | increased gastric motility and emptying |
C. | glucagon secretion |
D. | secretion of pancreatic juice |
Answer» B. increased gastric motility and emptying |
8. |
Which hormone is most important in insulin secretion? |
A. | gastrin |
B. | CCK |
C. | GIP |
D. | secretin |
Answer» C. GIP |
9. |
Which produces the majority of salivary volume? |
A. | lingual glands |
B. | sublingual |
C. | parotid |
D. | submandibular |
Answer» D. submandibular |
10. |
Which nerve is NOT involved in the efferent (motor) swallow reflex? |
A. | trigeminal |
B. | vagus |
C. | facial |
D. | hypoglossal |
Answer» B. vagus |
11. |
Which is NOT part of the normal content of gastric juice? |
A. | HPO4 2- |
B. | mucus |
C. | lipase |
D. | amylase |
Answer» D. amylase |
12. |
Chief cells secrete: |
A. | HCl |
B. | pepsinogen |
C. | intrinsic factor |
D. | HCO3- |
Answer» B. pepsinogen |
13. |
Which stimulates parietal cell secretion? |
A. | prostaglandins |
B. | aspirin |
C. | vinegar |
D. | acetylcholine |
Answer» D. acetylcholine |
14. |
Regarding bilirubin: |
A. | unconjugated bilirubin is more soluble than conjugated |
B. | all conjugated bilirubin is excreted via the intestine |
C. | bile duct obstruction causes jaundice secondary to unconjugated hyperbilirubinaemia |
D. | haemolytic anaemia may cause ?????? hyperbilirubinaemia |
Answer» D. haemolytic anaemia may cause ?????? hyperbilirubinaemia |
15. |
Which form of intestinal smooth muscle contraction does NOT occur in normal health? |
A. | peristalsis |
B. | weak antiperistalsis |
C. | peristaltic rushes |
D. | tonic contractions |
Answer» C. peristaltic rushes |
16. |
In the adrenal medulla: |
A. | epinephrine is formed by the hydroxylation and decarboxylation of tyrosine |
B. | 10% of the cells are the epinephrine-secreting type |
C. | plasma norepinephrine levels are generally unchanged after adrenalectomy |
D. | catecholamine t1/2 is 10 minutes in the circulation |
Answer» C. plasma norepinephrine levels are generally unchanged after adrenalectomy |
17. |
In the adrenal cortex: |
A. | the zona glomerulosa has 17 alpha-hydroxylase and no aldosterone synthase |
B. | all the cholesterol is synthesised from acetate |
C. | zona fasciculata makes up 10% of the mass of the adrenal gland |
D. | angiotensin II binds to receptors in the zona reticularis |
Answer» E. |
18. |
Regarding the islets of Langerhans: |
A. | D cells secrete pancreatic polypeptide |
B. | A cells are the most common |
C. | they are most plentiful in the body of the pancreas |
D. | blood from the islets drain into the hepatic portal vein |
Answer» D. blood from the islets drain into the hepatic portal vein |
19. |
Which factor stimulates insulin secretion? |
A. | thiazide diuretics |
B. | phenytoin |
C. | theophylline |
D. | β blockers |
Answer» C. theophylline |
20. |
Thyroid hormones increase the oxygen consumption of: |
A. | lymph nodes |
B. | spleen |
C. | brain |
D. | anterior pituitary gland |
Answer» E. |
21. |
The action of gastrin includes all EXCEPT: |
A. | stimulation of insulin secretion after a carbohydrate meal |
B. | stimulation of gastric acid secretion |
C. | stimulation of gastric motility |
D. | contraction of gastro-oesophageal junction musculature |
Answer» A. stimulation of insulin secretion after a carbohydrate meal |
22. |
Regarding protein metabolism, which statement is CORRECT? |
A. | increases the respiratory quotient to values > 1.0 |
B. | has a specific dynamic action (SDA) of approximately 10% |
C. | endogenous protein breakdown is inhibited by glucagon |
D. | creatinine excretion is not depressed in starvation |
Answer» D. creatinine excretion is not depressed in starvation |
23. |
Regarding fat metabolism, which statement is CORRECT? |
A. | ketone bodies accumulate in DKA due to a lack of acetyl-CoA substrate |
B. | fatty acids are transported in the plasma bound to lipoprotein complexes |
C. | cholesterol is transported from extra-hepatic cells to the liver by high-density lipoproteins (HDLs) in the endogenous pathway |
D. | eicosanoids are synthesised from cholesterol |
Answer» C. cholesterol is transported from extra-hepatic cells to the liver by high-density lipoproteins (HDLs) in the endogenous pathway |
24. |
Thyroxine: |
A. | is mostly bound to albumin in the plasma, since this has the largest capacity |
B. | is 2-5 times more potent that triiodothyronine (T3) |
C. | stimulates TSH release |
D. | ∼33% is deiodinated in the liver to T3 |
Answer» D. ∼33% is deiodinated in the liver to T3 |
25. |
Insulin: |
A. | binds to GLUT 1-5 receptors in the peripheral tissues |
B. | deficiency results in increased gluconeogenesis |
C. | has a plasma half-life of 2-3 hours |
D. | is secreted by the pancreatic A cells |
Answer» E. |
26. |
With respect to calcium metabolism / bone formation: |
A. | osteoclasts secrete alkaline phosphatase |
B. | osteoblasts are haemopoietic derivatives of monocyte lineage |
C. | 1,25(OH)2 ???D3 and PTH stimulate both osteoblasts and osteoclasts |
D. | oestrogens are thought to be protective of osteoporosis as their main effect is osteoblasts stimulation |
Answer» C. 1,25(OH)2 ???D3 and PTH stimulate both osteoblasts and osteoclasts |
27. |
All of the following, except one, inhibit insulin secretion. Which is it? |
A. | somatostatin |
B. | thiazide diuretics |
C. | propranolol |
D. | insulin |
Answer» E. |
28. |
All but one of the following compounds releases large amounts of energy on breakdown: |
A. | cAMP |
B. | ATP |
C. | creatine phosphate |
D. | ADP |
Answer» A. cAMP |
29. |
Which is TRUE? |
A. | adenosine triphosphate is a low energy phosphate |
B. | reduction involves loss of hydrogen or electrons |
C. | oxidative phosphorylation occurs in the endoplasmic reticulum |
D. | ATP is precursor of cyclic AMP |
Answer» D. ATP is precursor of cyclic AMP |
30. |
Small intestine: |
A. | the ligament of Treitz the jejunum becomes the ileum |
B. | the distance pylorus to ileocecal valve in living humans is 700cm |
C. | malabsorption syndrome may develop if 25% of the small intestine is removed |
D. | colonic peristalsis is the first smooth muscle action of the GIT to return after abdominal operation |
Answer» E. |
31. |
Regarding thyroid hormones: |
A. | little T3 is produced peripherally by deiodination T4 |
B. | albumin has more capacity to bind thyroid hormones than TBG |
C. | TBG has less affinity for thyroid hormone than albumin |
D. | thyroid hormones stimulate lipogenesis |
Answer» B. albumin has more capacity to bind thyroid hormones than TBG |
32. |
A calorie is: |
A. | standard unit of heat energy necessary to raise the temperature of 1L of water 1° from 15-16°C |
B. | standard unit of heat energy necessary to raise the temperature of 1gm of mercury 1° from 17-18°C |
C. | the standard unit of heat energy necessary to raise the temperature of 1gm of water 1° from 17-18°C |
D. | the standard unit of heat energy necessary to raise the temperature of 1gm of water 1° from 15-16°C |
Answer» D. the standard unit of heat energy necessary to raise the temperature of 1gm of water 1° from 15-16°C |
33. |
Regarding the respiratory quotient: |
A. | it is the ratio of CO2 to O2 at any time |
B. | RQ of fat is 0.8 |
C. | increases with hyperventilation |
D. | increases in metabolic alkalosis |
Answer» E. |
34. |
Regarding basal metabolic rate: |
A. | it is higher in women |
B. | it is determined at rest within 12 hours after the last meal |
C. | increases by 18% for each 1°C of fever |
D. | is about 40Kcal/m2/h in an average man |
Answer» D. is about 40Kcal/m2/h in an average man |
35. |
Which is NOT a high energy compound? |
A. | CoA |
B. | GGP |
C. | ITP |
D. | creatine phosphate |
Answer» B. GGP |
36. |
Regarding carbohydrate metabolism: |
A. | glucokinase is increased in starvation |
B. | the breakdown of glycogen is called glycolysis |
C. | the direct oxidative pathway involves the breakdown of glucose through triose |
D. | the conversion of pyruvate to acetyl-CoA is irreversible |
Answer» D. the conversion of pyruvate to acetyl-CoA is irreversible |
37. |
Which is NOT produced by the citric acid cycle? |
A. | NAD+ |
B. | CO2 |
C. | GTP |
D. | FADH2 |
Answer» A. NAD+ |
38. |
Regarding phosphorylase: |
A. | it clea???? 1:6α linkages in glycogen |
B. | it is activated by norepinephrine |
C. | phosphorylase kinase is directly activated by cyclic AMP |
D. | activation of protein kinase A inhibits glycogen synthesis |
Answer» D. activation of protein kinase A inhibits glycogen synthesis |
39. |
Which amino acid is not found in protein? |
A. | ornithine |
B. | arginine |
C. | valine |
D. | aspartic acid |
E. | β-Alanine |
Answer» E. β-Alanine |
40. |
Regarding electrolyte absorption: |
A. | cholera toxin binds to adenosine diphosphate ribose to the subunit of Gs, stimulative ATPase activity |
B. | active transport of Na+ into the small intestine enterocytes is coupled with the absorption of glucose |
C. | magnesium sulphate absorption is coupled with Na+ -K+ -ATPase pump |
D. | the Na+ -K+ ATPase pumps are located at the luminal membrane of the enterocyte |
Answer» E. |
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