McqMate
| 1. |
Which one of these is responsible for hardness of tablet? |
| A. | Die Filling |
| B. | Compression force |
| C. | Both (a) & (b) |
| D. | None of these |
| Answer» C. Both (a) & (b) | |
| 2. |
Crown thickness of the tablet is measured by |
| A. | Micrometer |
| B. | Hydrometer |
| C. | Pychnometer |
| D. | Any one of the above |
| Answer» C. Pychnometer | |
| 3. |
Friablilator is operated for _________ revolutions per minute. |
| A. | 100 |
| B. | 75 |
| C. | 50 |
| D. | 25 |
| Answer» A. 100 | |
| 4. |
In dissolution test, flask is maintained at: |
| A. | 31° C ± 0.5C |
| B. | 41° C ± 0.1C |
| C. | 39° C ± 0.6C |
| D. | 40° C ± 0.1C |
| Answer» A. 31° C ± 0.5C | |
| 5. |
Enteric coated tablet disintegrate in ____ hrs in simulated intestinal fluid. |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» B. 2 | |
| 6. |
Separation of tablet in 2 or more distinct layer is |
| A. | Capping |
| B. | Mottling |
| C. | Lamination |
| D. | Air entrapment |
| Answer» C. Lamination | |
| 7. |
Capping is prevented by using: |
| A. | Flat |
| B. | Circular |
| C. | Square |
| D. | Rectangular |
| Answer» A. Flat | |
| 8. |
Plating of punch forces is done by: |
| A. | Chromium |
| B. | Zinc |
| C. | Iron |
| D. | Any of the above |
| Answer» A. Chromium | |
| 9. |
Unequal distribution of color is called |
| A. | Capping |
| B. | Lamination |
| C. | Mottling |
| D. | None of the above |
| Answer» C. Mottling | |
| 10. |
________ is directly compressible excipient |
| A. | Spray Dried lactose |
| B. | Dibasic calcium phosphate |
| C. | None of the above |
| D. | Any of the above |
| Answer» A. Spray Dried lactose | |
| 11. |
Sta-Rx-1500 contain ______ % of moisture |
| A. | 15 |
| B. | 10 |
| C. | 18 |
| D. | 50 |
| Answer» B. 10 | |
| 12. |
pH of small intestine is |
| A. | 1-2 |
| B. | 3-4 |
| C. | 6 |
| D. | 7-8 |
| Answer» D. 7-8 | |
| 13. |
Perforated pan is used for |
| A. | Sugar coating |
| B. | Film coating |
| C. | Both (a) & (b) |
| D. | None of the above |
| Answer» C. Both (a) & (b) | |
| 14. |
Subcoating is done to |
| A. | Round the edges |
| B. | Increase in the bulk of tablet |
| C. | Both (a) & (b) |
| D. | Make water resistant |
| Answer» C. Both (a) & (b) | |
| 15. |
Which one is the example of Opacifier |
| A. | TiO2 |
| B. | MgO |
| C. | Silicates |
| D. | None of the above |
| Answer» A. TiO2 | |
| 16. |
Empty capsule has moisture content in the range of |
| A. | 60% |
| B. | 12-15% |
| C. | 50-70% |
| D. | 30% |
| Answer» C. 50-70% | |
| 17. |
Which machine is designed for filling of pellets? |
| A. | Rotofil |
| B. | Rotosort |
| C. | Ordinary machine |
| D. | None of these |
| Answer» A. Rotofil | |
| 18. |
Soft gelatin capsule should not contain more than ____ ppm of iron as impurity? |
| A. | 5 |
| B. | 15 |
| C. | 40 |
| D. | 60 |
| Answer» B. 15 | |
| 19. |
Enteric resin used for coating is? |
| A. | Cellulose acetate Pthalate |
| B. | Zein |
| C. | Shellac |
| D. | All of the above |
| Answer» C. Shellac | |
| 20. |
Base for chewable tablets include |
| A. | Mannitol |
| B. | Glucose |
| C. | Lactose |
| D. | None |
| Answer» A. Mannitol | |
| 21. |
Enteric coated tablet disintegrate in |
| A. | Stomach |
| B. | Liver |
| C. | Intestine |
| D. | Mouth |
| Answer» C. Intestine | |
| 22. |
Not used as tablet glidant: |
| A. | Colloidal Silica |
| B. | Starch |
| C. | Talc |
| D. | Magnesium stearate |
| Answer» B. Starch | |
| 23. |
Rotosort is used for |
| A. | Sorting filled capsules |
| B. | Filling the capsule |
| C. | Mixing of powder |
| D. | None of the above |
| Answer» A. Sorting filled capsules | |
| 24. |
Hardness of tablet is measured by |
| A. | Pfizer tester |
| B. | Erweka Tester |
| C. | Strong Cobb |
| D. | All of the above |
| Answer» D. All of the above | |
| 25. |
Whiskering (a tablet defect) is observed with the use of _____ punch. |
| A. | Convex |
| B. | Flat |
| C. | Concave |
| D. | Biconvex |
| Answer» C. Concave | |
| 26. |
Shells of gelatin capsules is made elastic by adding |
| A. | Sorbitol |
| B. | PEG |
| C. | Povidone |
| D. | Lactose |
| Answer» A. Sorbitol | |
| 27. |
A retardant material that forms a hydrophilic matrix in the formulation of matrix tablet |
| A. | HPMC |
| B. | CAP |
| C. | Polyethylene |
| D. | Carnuba Wax |
| Answer» D. Carnuba Wax | |
| 28. |
How much amount is accepted to dissolve in a dissolution medium in 20 minute at 50 rpm? |
| A. | Not less than 70% |
| B. | Not more than 80% |
| C. | Not less than 80% |
| D. | 80% |
| Answer» C. Not less than 80% | |
| 29. |
What’s the role of cam tracks in tablet compression machines? |
| A. | For proper movement of the punches |
| B. | For proper movement of the granules |
| C. | For proper movement of both (granules and punches) |
| D. | For movement of granules and hopper |
| Answer» A. For proper movement of the punches | |
| 30. |
Which tablet compression machine is best for compression of granules? |
| A. | Single Press |
| B. | Longitudinal Press |
| C. | Rotary Press |
| D. | Stamping press |
| Answer» C. Rotary Press | |
| 31. |
Low melting point substances causes processing problem in tablets. Identify it. |
| A. | Poor Flow |
| B. | Weight variation |
| C. | Sticking |
| D. | Picking |
| Answer» C. Sticking | |
| 32. |
Which capsule size number has the maximum capacity? |
| A. | 5 |
| B. | 1 |
| C. | 0 |
| D. | 000 |
| Answer» D. 000 | |
| 33. |
Gelatin and glycerin are used for the preparation of lamellae in a specified ratio. Identify the correct ratio. |
| A. | 1:1 |
| B. | 5:1 |
| C. | 9:1 |
| D. | 10:1 |
| Answer» C. 9:1 | |
| 34. |
The 000 size capsules can fill the volume of: |
| A. | 1.36 ml |
| B. | 0.13 ml |
| C. | 0.96 ml |
| D. | 0.25 ml |
| Answer» A. 1.36 ml | |
| 35. |
Which of the following material is not used in extrusion? |
| A. | Wax |
| B. | Granules |
| C. | Powders |
| D. | Pellets |
| Answer» A. Wax | |
| 36. |
What is the name of the phase transition that occurs when a solid is converted directly into a gas (without going through the liquid phase)? |
| A. | Melting |
| B. | Boiling |
| C. | Condensing |
| D. | Sublimation |
| Answer» D. Sublimation | |
| 37. |
_______ is used for bulk handling, warehouse storage and transport shipping. The most common form is a palletized unit load that packs tightly into containers. |
| A. | Primary packaging |
| B. | Tertiary packaging |
| C. | Quaternary packaging |
| D. | Secondary packaging |
| Answer» B. Tertiary packaging | |
| 38. |
Packaging Testing includes: |
| A. | Shock test and drop test |
| B. | Vibration test |
| C. | Inclined Impact test |
| D. | All of the above |
| Answer» D. All of the above | |
| 39. |
Disadvantages of plastic material in packaging? |
| A. | Release alkali to aqueous preparation |
| B. | It is fragile so easily broken |
| C. | They react with certain chemicals |
| D. | Absorption permeable to moisture |
| Answer» D. Absorption permeable to moisture | |
| 40. |
Iron oxide, magnesium dioxide and chromium dioxide is the composition of ______ colored glass use in pharmaceutical packaging? |
| A. | Yellow |
| B. | Blue |
| C. | Green |
| D. | Amber |
| Answer» C. Green | |
| 41. |
Treated Soda lime glass is called as: |
| A. | Type I |
| B. | Type II |
| C. | Type III |
| D. | NP- Non Parentral |
| Answer» B. Type II | |
| 42. |
Powered glass test used for the standardization of which type of glass material: |
| A. | Type I, II & III |
| B. | Type I, III, IV |
| C. | Type II, III, IV |
| D. | All of the above |
| Answer» B. Type I, III, IV | |
| 43. |
Correct test for standardization of rubber material |
| A. | Leakage test/ Collapsibility |
| B. | Powder glass test |
| C. | Fragmentation test |
| D. | Hydraulic test |
| Answer» C. Fragmentation test | |
| 44. |
The main aim of package inserts or leaflets is: |
| A. | To provide information essential for the safe and effective use of the drugs |
| B. | Reducing the number of adverse reactions |
| C. | Adequate direction of use |
| D. | All of the above |
| Answer» D. All of the above | |
| 45. |
“Blue” color coding is used for which class of pharmaceutical products? |
| A. | Miotics |
| B. | Beta blockers |
| C. | NSAIDS |
| D. | Analgesic |
| Answer» A. Miotics | |
| 46. |
“Tan” color coding is used for which class of pharmaceutical products? |
| A. | Miotics |
| B. | Beta blockers |
| C. | NSAIDS |
| D. | Anti infectives |
| Answer» D. Anti infectives | |
| 47. |
“Orange” color coding is used for which class of pharmaceutical products? |
| A. | Antibiotics |
| B. | Beta blockers |
| C. | NSAIDS |
| D. | Anti-infectives |
| Answer» A. Antibiotics | |
| 48. |
“Pink” color coding is used for which class of pharmaceutical products? |
| A. | Antibiotics |
| B. | Beta blockers |
| C. | Steroids |
| D. | Anti-infectives |
| Answer» C. Steroids | |
| 49. |
Select the equation that gives the rate of drug dissolution from a tablet: |
| A. | Fick’s Law |
| B. | Henderson-Hasselbatch equation |
| C. | Noyes-Whitney equation |
| D. | Michaelis Menton equation |
| Answer» C. Noyes-Whitney equation | |
| 50. |
How many tablets require for content uniformity test |
| A. | 10 |
| B. | 20 |
| C. | 30 |
| D. | 40 |
| Answer» C. 30 | |
| 51. |
Enteric coated tablet is dissolved in 0.1 N HCl as per I.P. |
| A. | 180 minutes |
| B. | 120 minutes |
| C. | 45 minutes |
| D. | 60 minutes |
| Answer» B. 120 minutes | |
| 52. |
During compression, entrapped air may lead to: |
| A. | Capping & lamination |
| B. | Picking & sticking |
| C. | Binding & sticking |
| D. | Ejection & Removal |
| Answer» A. Capping & lamination | |
| 53. |
Anhydrous lactose has advantage over hydrous lactose. |
| A. | Improved flow |
| B. | Absence of milliard reaction |
| C. | Improved Compressibility |
| D. | High microbial load |
| Answer» B. Absence of milliard reaction | |
| 54. |
If the dose of the drug is inadequate, then it generally requires the following one, to make up its bulk: |
| A. | Binders |
| B. | Disintegrants |
| C. | Lubricants |
| D. | Diluents |
| Answer» D. Diluents | |
| 55. |
The first and most widely used diluent in tablet formulation is |
| A. | Dextrose |
| B. | Lactose |
| C. | MCC |
| D. | Starch |
| Answer» B. Lactose | |
| 56. |
Which of the following is a synthetic adhesive? |
| A. | PVP |
| B. | MC |
| C. | HPMC |
| D. | HPC |
| Answer» A. PVP | |
| 57. |
Which of the following packaging is commonly used for packaging of capsules? |
| A. | Blister |
| B. | Strip |
| C. | Both |
| D. | None |
| Answer» C. Both | |
| 58. |
Which of the following is used to fill powdered dry solid into soft gelatin capsules? |
| A. | Accogel |
| B. | Rotofil |
| C. | Rotosort |
| D. | Rotoweigh |
| Answer» A. Accogel | |
| 59. |
Sealing of capsules is achieved by: |
| A. | 100 °C |
| B. | 20 °C |
| C. | 37 °C – 40 °C |
| D. | 70 °C |
| Answer» C. 37 °C – 40 °C | |
| 60. |
Find the correct one. |
| A. | 000 largest size |
| B. | 00 Largest size |
| C. | 5 smallest size |
| D. | Both A and C are correct |
| Answer» D. Both A and C are correct | |
| 61. |
Which is a capsule filling machine? |
| A. | Osaka |
| B. | Jaansan |
| C. | Macofar |
| D. | All of the above |
| Answer» D. All of the above | |
| 62. |
Iron content of gelatin for hard and soft gelatin capsule: |
| A. | NMT 5 ppm |
| B. | NMT 10 ppm |
| C. | NMT 25 ppm |
| D. | NMT 15 ppm |
| Answer» D. NMT 15 ppm | |
| 63. |
Gelatin is hydrolysed product: |
| A. | Pectin |
| B. | Tannin |
| C. | Shellac |
| D. | Collagen |
| Answer» D. Collagen | |
| 64. |
Moisture content of capsule is determined by: |
| A. | IR Spectroscopy |
| B. | Toulene distillation method |
| C. | Accogel machine |
| D. | Erweka key |
| Answer» B. Toulene distillation method | |
| 65. |
____________ treatment is used for the solubility of gelatin. |
| A. | Heat |
| B. | Formalin |
| C. | Alcohol |
| D. | Formalin |
| Answer» B. Formalin | |
| 66. |
Type A gelatin has its isoelectric point in the region of |
| A. | pH 4.7 |
| B. | pH 9.0 |
| C. | pH 7.4 |
| D. | pH 9.4 |
| Answer» B. pH 9.0 | |
| 67. |
In capsules, Elancofil and accofil machine is used for |
| A. | Filling of powder into capsules |
| B. | Filling pellets into capsules |
| C. | Sorting filled capsule |
| D. | Filling liquids into capsules |
| Answer» A. Filling of powder into capsules | |
| 68. |
In capsules, Qualiseal machine is used for: |
| A. | Sorting the filled capsules |
| B. | Filling the liquids into capsules |
| C. | Filling pellets into capsules |
| D. | Filling powder into capsules |
| Answer» B. Filling the liquids into capsules | |
| 69. |
Sulphur dioxide is used for: |
| A. | As a coloring agent |
| B. | To prevent bitterness |
| C. | To prevent decomposition of gelatin shell |
| D. | None of the above |
| Answer» C. To prevent decomposition of gelatin shell | |
| 70. |
Green bones are used for the preparation of gelatin of the type: |
| A. | Type A |
| B. | Type B |
| C. | Type C |
| D. | A & B |
| Answer» B. Type B | |
| 71. |
Viscosity of gelatin ranges from: |
| A. | 8-10 millipoise |
| B. | 60-80 millipoise |
| C. | 2-10 millipoise |
| D. | 25-45 millipoise |
| Answer» D. 25-45 millipoise | |
| 72. |
The approximate particle size of microcapsule using solvent evaporation is: |
| A. | 5-5000 µm |
| B. | 100-10,000 µm |
| C. | 10-100 µm |
| D. | 5-10 µm |
| Answer» A. 5-5000 µm | |
| 73. |
Which of the following is a tamper proof dosage form? |
| A. | Tablet |
| B. | Capsule |
| C. | Dry powder |
| D. | Syrup |
| Answer» A. Tablet | |
| 74. |
Weight variation limits as per USP for the tablet weight more than 324 mg: |
| A. | 7.5 mg |
| B. | 7.5% |
| C. | 5% |
| D. | 5 mg |
| Answer» C. 5% | |
| 75. |
Apparatus 1 as per USP: |
| A. | Flow-through cell |
| B. | Paddle |
| C. | Basket |
| D. | Reciprocating cylinder |
| Answer» C. Basket | |
| 76. |
What is different in B tooling and D tooling? |
| A. | Punch and die length are different |
| B. | Punch length same but die length different |
| C. | Punch and die diameter are different |
| D. | Punch diameter same but die diameter different |
| Answer» C. Punch and die diameter are different | |
| 77. |
Ratio of methyl paraben and propyl paraben used as preservative in capsule? |
| A. | 4:1 |
| B. | 1:4 |
| C. | 1:2 |
| D. | 1:1 |
| Answer» A. 4:1 | |
| 78. |
Dispirin is a? |
| A. | Dispersible tablet |
| B. | Soluble tablet |
| C. | Effervescent tablet |
| D. | None of the above |
| Answer» A. Dispersible tablet | |
| 79. |
For Sugar Coated tablet, the specified disintegration time is: |
| A. | 60 min. |
| B. | 120 min. |
| C. | 30 min. |
| D. | 15 min. |
| Answer» A. 60 min. | |
| 80. |
Adhesion of tablet material to die wall is called: |
| A. | Sticking |
| B. | Picking |
| C. | Capping |
| D. | Mottling |
| Answer» A. Sticking | |
| 81. |
Which of the following is responsible for sticking? |
| A. | Excessive moisture |
| B. | Low moisture |
| C. | Both |
| D. | None |
| Answer» A. Excessive moisture | |
| 82. |
Which of the following is not a commercially available Starch product? |
| A. | Sta-Rx 1500 |
| B. | Celutab |
| C. | Emdex |
| D. | Sugar tab |
| Answer» D. Sugar tab | |
| 83. |
Aerosil is used as a: |
| A. | Glidant |
| B. | Lubricant |
| C. | Antiadherent |
| D. | None |
| Answer» A. Glidant | |
| 84. |
Tablets that are placed between cheek and teeth are known as: |
| A. | Buccal |
| B. | Sublingual |
| C. | Lozenges |
| D. | Troches |
| Answer» A. Buccal | |
| 85. |
Flow rate of granules from the hopper can be improved by adding: |
| A. | Disintegrants |
| B. | Glidants |
| C. | Binders |
| D. | Lubricant |
| Answer» B. Glidants | |
| 86. |
The aim of Sub-coating is: |
| A. | To increase the bulkiness |
| B. | To avoid deterioration due to microbial attack |
| C. | To prevent solubility in acidic medium |
| D. | To avoid stickiness |
| Answer» A. To increase the bulkiness | |
| 87. |
The following ingredients are commonly used as coating agents for film coating except: |
| A. | CAP |
| B. | Carnuba Wax |
| C. | HEC |
| D. | Sodium CMC |
| Answer» B. Carnuba Wax | |
| 88. |
The Wurster process can be used for: |
| A. | Coating |
| B. | To determine disintegration time |
| C. | Gas sterilize parenteral solution |
| D. | Automatic filling of capsules |
| Answer» A. Coating | |
| 89. |
In tablet formulation, PVP is used mainly as: |
| A. | Glidant |
| B. | Diluent |
| C. | Lubricant |
| D. | Binder |
| Answer» D. Binder | |
| 90. |
Use of cross povidone in tablet formulation: |
| A. | Binder |
| B. | Disintegrant |
| C. | Flow enhancer |
| D. | Lubricant |
| Answer» B. Disintegrant | |
| 91. |
Use of colloidal silicone dioxide in tablet formulation: |
| A. | Diluent |
| B. | Disintegrant |
| C. | Glidant |
| D. | Lubricant |
| Answer» C. Glidant | |
| 92. |
Boxes and cartons are covered in which type of packaging in pharmaceutical? |
| A. | Primary |
| B. | Secondary |
| C. | Tertiary |
| D. | Quaternary |
| Answer» B. Secondary | |
| 93. |
____________ is the best pharmaceutical packaging film for tablets, capsules, which is taking place of PVC film. |
| A. | Ply bean foil |
| B. | Quick sol foil |
| C. | Silly-silly foil |
| D. | Alu-alu foil |
| Answer» D. Alu-alu foil | |
| 94. |
Which of the following polymer is widely used in film coating of tablets? |
| A. | Acacia |
| B. | Syrup |
| C. | HPMC |
| D. | Starch |
| Answer» C. HPMC | |
| 95. |
Lamination is: |
| A. | Separation of a tablet into two or more distinct layer |
| B. | Partial & complete separation of top & bottom crowns of the tablet from the main body of the tablet |
| C. | Process of sub-coating |
| D. | None of the above |
| Answer» A. Separation of a tablet into two or more distinct layer | |
| 96. |
Seal coat aim is to: |
| A. | To prevent moisture deposition |
| B. | To round the edge and build the tablet size |
| C. | To smoothen the surface |
| D. | To prevent the tablet from breaking due to vibration |
| Answer» A. To prevent moisture deposition | |
| 97. |
Which of the following ingredient is used for polishing of sugar coated tablets |
| A. | Gelatin |
| B. | Talc |
| C. | PEG 4000 |
| D. | Carnauba wax |
| Answer» D. Carnauba wax | |
| 98. |
____________ decreases the bioavailability of tetracycline. |
| A. | Lactose |
| B. | DCP |
| C. | Starch |
| D. | MCC |
| Answer» B. DCP | |
| 99. |
The first stage of wetting on addition of a granulating agent to the powders is characterized by which one of the followings? |
| A. | Capillary state |
| B. | Pendular state |
| C. | Funicular state |
| D. | Droplet state |
| Answer» A. Capillary state | |
| 100. |
Larger values of Ky in the Heckel Plot indicate formation of what quality of tablets? |
| A. | Harder tablets |
| B. | Soft tablets |
| C. | Brittle tablets |
| D. | Fluffy tablets |
| Answer» A. Harder tablets | |
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