Q.

Regarding the “azole” group of antifungals

A. Fluconazole has low water solubility
B. Ketoconazole may be given IV/PO
C. Itraconazole undergoes renal elimination
D. Clotrimazole is the treatment of choice for systemic candidiasis – given orally
E. They work by reduction of ergosterol synthesis by inhibition of fungal cytochrome P450 enzymes
Answer» E. They work by reduction of ergosterol synthesis by inhibition of fungal cytochrome P450 enzymes
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