Q.

With respect to opioid receptors

A. Fentanyl works predominantly at the kappa receptors
B. Both U and delta receptors contribute to respiratory depression
C. Methadone is used for heroin withdrawal because its actions are predominantly at the delta receptors
D. Opioid receptors are coupled to a tyrosine kinase mechanism of action
E. Physical dependence and tolerance is caused by the rapid disintegration of receptors
Answer» B. Both U and delta receptors contribute to respiratory depression
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