McqMate
| Q. |
Which of the following characteristics is suitable for transdermal drug? |
| A. | large drug dose |
| B. | large molecular size |
| C. | drugs with narrow therapeutic indices |
| D. | drugs which are metabolized in the skin |
| Answer» C. drugs with narrow therapeutic indices | |
| Explanation: the transdermal route is unsuitable when the drug dose is large when the drug has a large molecular size, the drug is skin sensitizing and irritating. it also becomes a problem when the drug is metabolized in the skin, the drug goes protein binding in the skin, or even if the drug is highly lipophilic or hydrophilic. | |
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