Hydrophobic drug with fine particle size in capsule results in a decreasing porosity of powder bed.

Related MCQs

• In the case of hydrophobic drugs, micronization results in a decrease in effective surface area and thus fall is dissolution rate. Which of the below sentences cannot be a reason for the given statement?
• How the absolute surface area of hydrophobic drugs can be converted to their effective surface area?
• In cell membrane the hydrocarbon chains for hydrophilic phase and the polar heads form hydrophobic phase.
• Under the concept biopharmaceutics, hydrophobic drugs are
• Particle size and surface area of a drug are directly related to each other.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• Following is the order in decreasing order of drug binding to the extravascular tissue. Which one is the correct order?
• What will be the particle size after micronization of drugs?