Q.

Regarding uric acid, which statement is INCORRECT?

A. the majority of filtered uric acid is reabsorbed in the proximal tubule
B. xanthine oxidase catalyses its synthesis
C. may be elevated in leukaemia and pre-eclampsia
D. does not undergo renal tubular secretion
E. its excretion rate can be halved by changing to a purine-free diet
Answer» D. does not undergo renal tubular secretion
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