Mutations of the p53 gene frequently occur in:

Related MCQs

• Mutations in which gene are least likely to be associated with breast cancer if inherited in the germ-line?
• A 64-year-old woman has the following family history: One sister, who was a smoker, had lung cancer at the age of 63 years; another sister had breast cancer at the age of 70 years. Her father had prostate cancer at 82 years of age, and her mother had breast cancer at age 71 years. She has three other sisters, now aged 58, 60, and 65 years who have no history of cancer. She has two daughters and two sons between the ages of 25 and 39 years, who have no history of cancer. Her ancestry is European in general, and she is not of known Ashkenazi Jewish descent. She is concerned that “cancer runs in the family” and would like to have one of those “gene tests” she has read about. What is the best advice to give her and her family?
• During gene therapy, genes are most commonly transferred into cells by:
• Which of the following cell cycle phase transitions is most affected when the TP53 gene is lost or mutated?
• Which neoplasm is most FREQUENTLY found in the appendix?
• Which of the following types of cancer is most frequently associated with isolated hepatic metastases at presentation?
• The carcinoid syndrome is likely to occur with carcinoid tumors:
• Which of the following is least to occur as Gallbladder primary?
• All of the following can occur in germ line leading to breast cancer except which one: