Only unbound or free drug is capable of being eliminated.

Related MCQs

• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• Which one is the correct equation to calculate fraction of unbound drug in plasma?
• For a drug that is eliminated primarily by renal glomerular filtration, the theoretical maximum clearance is approximately
• The half life of a drug eliminated by first order elimination kinetics will be longer in individuals who have an:
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• If drug administered by Intravenous route appears in feaces, it implies that the drug
• If drug has pKa value of 3 then at pH value of 7 what would be the degree of ionisation of the drug?
• The occurrence of food in the GI tract can affect the drug bioavailability from an oral drug product. The above give statement is?
• According to pH partition theory, a weak acidic drug will most likely be absorbed from the stomach because the drug which exists primarily in the………….