Which one is the correct equation to calculate fraction of unbound drug in plasma?

Related MCQs

• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• Only unbound or free drug is capable of being eliminated.
• If the drug Y bind with plasma albumin with 10 times more affinity than drug X. Which the given statement is true?
• The amount of drug in the body is directly proportional to the concentration of the drug in plasma.
• The urinary excretion of the unchanged drug is directly proportional to the plasma concentration of a drug.
• The renal clearance of a drug bound to plasma protein is increased after displacement with another drug.
• Penicillin has short plasma half-life although it can bind to plasma protein rigidly.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.