A 54-year-old woman comes to the physician for an annual examination. She has no complaints. For the past year, she has been taking tamoxifen for the prevention of breast cancer. She was started on this drug after her physician determined her to be at high risk on the basis of her strong family history, nulliparity, and early age at menarche. She takes no other medications. Examination is within normal limits. Which of the following is this patient most likely to develop while taking tamoxifen?

A. Breast cancer
B. Elevated LDL cholesterol
C. Endometrial changes
D. Myocardial infarction
E. Osteoporosis
Answer» C. Endometrial changes
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