Mechanism of drug resistance of chemotherapeutic drugs

Related MCQs

• A 40-year-old woman has a routine gynecologic examination. At the age of 32 years, she gave birth to twins after receiving fertility drugs. She has just seen a television program on ovarian cancer, and is concerned because previous use of fertility drugs and a family history of ovarian cancer were mentioned as possible risk factors. Her mother developed endometrial cancer at 56 years, and a paternal uncle was diagnosed with a type of lymphoma at 60 years. She has one older sister with hypertension and one younger brother who is healthy. Results of her pelvic examination are unremarkable, but she asks what additional tests she should have to look for ovarian cancer in the early stages that cannot be detected by physical examination. What is the most appropriate management for this patient?
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• The most common mechanism of spread of epithelial ovarian cancer is:
• Which of the following chemotherapy drug is likely to be toxic to gonads?
• Patient with germ cell tumor receiving BEP. Which side-effect would necessitate cessation of the responsible drug:
• Phase 2 trial of new cancer drug. Which is least likely to account for variation in results:
• Patient gets bleomycin, etoposide, and cisplatin. Which cause for cessation of specific drug?
• Which drug is least likely to affect cytokine production - especially IL-2 in T cells?