The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. This is known as ____________

Related MCQs

• Bioequivalence is a relative term which denotes that the drug substance reaches the systemic circulation at the same relative rate or time.
• Which of the following process drug moves from site of administration to systemic circulation?
• ………………is the process of movement of unchanged drug from the site of administration to the systemic circulation.
• The relative amount of an administered dose that reaches the general circulation and the rate at which this occurs.
• The compartment models provide visual representation of various rate processes involved in drug disposition. Given statement is:
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• Which of the following will be the slowest step in tablet drug absorption?
• What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.