The compartment models provide visual representation of various rate processes involved in drug disposition. Given statement is:

Related MCQs

• Which organs comprise the central compartment in a two compartment model?
• Which organ comprises the peripheral compartment in a two compartment model?
• The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. This is known as ____________
• A multicompartment model assumes that all transfer rate processes for the passage of drug into or out of individual compartments are…………….. processes.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?
• If the drug Y bind with plasma albumin with 10 times more affinity than drug X. Which the given statement is true?
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• If the pH of either side of the membrane is different, then the compartment whose pH favours greater ionization will have less amount of drug.