Multiple dose study is better since we can understand the peak, valley, drug blood levels, etc.

Related MCQs

• ………………… is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• Concentration of drug at peak is known as …………drug concentration.
• ……………composed of groups of tissues with lower blood perfusion and different affinity the drug with slow drug distribution.
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• …………………it is the extent to which a drug will accumulate relative to the first dose can be quantified by an accumulation factor R.
• In…………..Pharmacokinetic parameters for a drug can change with change in dose.
• …………..it is the extent to which a drug will accumulate relative to the first dose can be quantified by an accumulation factor R.
• The loading dose of a drug is based upon the