…………..it is the extent to which a drug will accumulate relative to the first dose can be quantified by an accumulation factor R.

Related MCQs

• …………………it is the extent to which a drug will accumulate relative to the first dose can be quantified by an accumulation factor R.
• ………………… is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose.
• The extent of drug-protein binding can change with both changes in protein and drug concentration.
• Which drug accumulate in adipose tissue?
• Bioequivalence is a relative term which denotes that the drug substance reaches the systemic circulation at the same relative rate or time.
• Accumulation occurs because drug from previous doses was not being removed completely.
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• Multiple dose study is better since we can understand the peak, valley, drug blood levels, etc.