Any changes in fraction bioavailable, elimination half-life indicates nonlinearity of that particular drug.

Related MCQs

• Which of the following creates nonlinearity in drug distribution and not in drug absorption?
• What is the equation of bioavailable fraction?
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• The extent of drug-protein binding can change with both changes in protein and drug concentration.
• If distribution of drug is slower than process of biotransformation and elimination
• Drug elimination involves....... (ADME are steps of pharmacokinetics)
• What will be the elimination rate if the clearance is 130ml/min and drug concentration is 0.8 g/ml?
• Drug showing zero order kinetic of elimination