Q.

Thiazide diuretics enhance K+ elimination in urine primarily by:

A. Inhibiting proximal tubular K+ reabsorption
B. Inhibiting Na+ K+-2Cl– cotransport in the ascending limb of loop of Henle
C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K+
D. Potentiating the action of aldosterone
Answer» C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K+
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