If the pH of either side of the membrane is different, then the compartment whose pH favours greater ionization will have less amount of drug.

Related MCQs

• Which organs comprise the central compartment in a two compartment model?
• Which organ comprises the peripheral compartment in a two compartment model?
• To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• In two compartment model, extravascular route of drug administration, there are ……phases
• The compartment models provide visual representation of various rate processes involved in drug disposition. Given statement is:
• The amount of drug in the body is directly proportional to the concentration of the drug in plasma.
• ……………composed of groups of tissues with lower blood perfusion and different affinity the drug with slow drug distribution.