Accumulation occurs because drug from previous doses was not being removed completely.

Related MCQs

• …………………it is the extent to which a drug will accumulate relative to the first dose can be quantified by an accumulation factor R.
• …………..it is the extent to which a drug will accumulate relative to the first dose can be quantified by an accumulation factor R.
• Factors altering the binding of the drug to the blood increases the volume of distribution of the drug and the factors that influence drug binding to the extravascular component decreases the volume of distribution.
• Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
• For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
• According to pH partition theory, a weak acidic drug will most likely be absorbed from the stomach because the drug which exists primarily in the………….
• According to pH partition theory, a weak acidic drug will most likely be absorbed from the stomach because the drug which exist primarily in the
• Which one of the following factor related to protein-drug binding is not related to drug interactions with the binding site?
• Which of the following creates nonlinearity in drug distribution and not in drug absorption?
• ………..is defined as volume of blood or plasma from drug is removed in unit time