Q.

Which of the following statements is the closest description of Phase I metabolism?

A. Reactions which add a polar molecule to a functional group already present on a drug or one of its metabolites
B. Reactions which occur in the blood supply.
C. Reactions which add a polar functional group to a drug.
D. Reactions which occur in the gut wall.
Answer» C. Reactions which add a polar functional group to a drug.
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Medicinal Chemistry 1

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