McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) , Pharmacy .
Chapters
| 1. |
Which of the following properties of a particle significantly affects the physical, chemical and biological properties of the drug? |
| A. | density |
| B. | sedimentation |
| C. | size |
| D. | surface area |
| Answer» D. surface area | |
| 2. |
It is difficult to express the size of particles in a meaningful diameter. |
| A. | irregular in shape |
| B. | irregular surface |
| C. | spherical shape |
| D. | uniform in size |
| Answer» A. irregular in shape | |
| 3. |
The type of a particle diameter obtained largely depends on: |
| A. | method by which it is determined |
| B. | nature of the powder |
| C. | procedure by which it is calculated |
| D. | way it is defined and described |
| Answer» A. method by which it is determined | |
| 4. |
When cumulative percent frequency on a probability scale is plotted against logarithm of the particle size, 50 percent on the probability scale gives the powder particle diameter of: |
| A. | arithmetic mean |
| B. | arithmetic mode |
| C. | geometric mean |
| D. | harmonic mean |
| Answer» C. geometric mean | |
| 5. |
Which one of these distributions is more important in the design of dosage forms? |
| A. | Gaussian |
| B. | normal |
| C. | number |
| D. | weight |
| Answer» D. weight | |
| 6. |
In the formulation development of emulsions and suspensions, what type of diameter is important? |
| A. | length number |
| B. | projected |
| C. | sieve |
| D. | stokes |
| Answer» D. stokes | |
| 7. |
Sieving method is used for size distribution analysis of powder. The disadvantage of this method is: |
| A. | agglomerates can be identified |
| B. | attrition of powder is possible |
| C. | large number of sieves are required |
| D. | tedious and time consuming |
| Answer» B. attrition of powder is possible | |
| 8. |
While using sedimentation method for size analysis, addition of a deflocculating agent to a suspension is necessary in order to: |
| A. | accelerate the process of sedimentation |
| B. | make the particles spherical |
| C. | prevent the aggregation |
| D. | satisfy Reynolds number |
| Answer» C. prevent the aggregation | |
| 9. |
Stokes’ law cannot be used, if Reynolds number is more than: |
| A. | 0.2 |
| B. | 1.8 |
| C. | 9.0 |
| D. | 18.0 |
| Answer» A. 0.2 | |
| 10. |
Andreasen apparatus consists of: |
| A. | balance |
| B. | electrodes |
| C. | hydrometer |
| D. | pipette |
| Answer» C. hydrometer | |
| 11. |
When coulter-counter apparatus is employed for powder analysis, the following criterion is important: |
| A. | dispersion medium should be colored |
| B. | dispersion medium should be conducting |
| C. | suspended particles should be charged |
| D. | suspended particles should be spherical |
| Answer» B. dispersion medium should be conducting | |
| 12. |
In coulter-counter, as the particles travel through the orifice, the event that occurs is: |
| A. | conductance between the electrodes increases |
| B. | electronic scanners produce photographs for volume measurement |
| C. | resistance between the electrodes increases |
| D. | sedimentation increases |
| Answer» C. resistance between the electrodes increases | |
| 13. |
Fisher subsieve sizer is used to determine the surface area of the powder. The surface area is measured based on the change in: |
| A. | light transmission of gas that reaches the detector |
| B. | pressure across the compacted powder |
| C. | thermal conductivity of gas across the powdered pack |
| D. | weight of powder when air is passed through the powdered pack |
| Answer» D. weight of powder when air is passed through the powdered pack | |
| 14. |
High repose angle of the granules indicated: |
| A. | bulk density of the granules |
| B. | porosity of the granules |
| C. | roughness of the granule surface |
| D. | smoothness of the granule surface |
| Answer» C. roughness of the granule surface | |
| 15. |
The true density of talc is 2.7 g/cc, the bulk density (g/cc) of talc will be: |
| A. | equal to 2.7 |
| B. | greater than 2.7 |
| C. | less than 2.7 |
| D. | unrelated |
| Answer» C. less than 2.7 | |
| 16. |
The angle of repose values are utilized to: |
| A. | measure the movement of granules from hopper to the table of tabletting/capsule machine |
| B. | select proper containers for capsules of a given mass of powders |
| C. | study the absorption of drugs |
| D. | understand dissolution of medicament |
| Answer» A. measure the movement of granules from hopper to the table of tabletting/capsule machine | |
| 17. |
The term ‘light’ as applied to pharmaceutical powders means: |
| A. | low bulk density |
| B. | low granule density |
| C. | low true density |
| D. | slightly coloured |
| Answer» B. low granule density | |
| 18. |
The type of particle diameter that is obtained by microscope method of evaluation is: |
| A. | projected |
| B. | stokes’ |
| C. | volume |
| D. | volume-surface |
| Answer» A. projected | |
| 19. |
Porosity of a porous powder is defined as: |
| A. | bulk volume/void volume |
| B. | void volume/bulk volume |
| C. | void volume/true volume |
| D. | true volume/bulk volume |
| Answer» B. void volume/bulk volume | |
| 20. |
Which equation is used to convert number distribution to weight distribution |
| A. | Noyes whitney equation |
| B. | Hatch Choate equation |
| C. | Henderson Hasselbalch equation |
| D. | Higuchi equation |
| Answer» B. Hatch Choate equation | |
| 21. |
Coulter counter is used to determine |
| A. | Particle volume |
| B. | Particle Number |
| C. | Particle interaction |
| D. | Viscosity |
| Answer» A. Particle volume | |
| 22. |
The ratio of void volume to bulk volume is known as |
| A. | Bulk density |
| B. | Tapped density |
| C. | Porosity |
| D. | Granule volume |
| Answer» A. Bulk density | |
| 23. |
If Carr's compressibility index value is in between 26 to 31, then flow will be |
| A. | Poor |
| B. | Excellent |
| C. | Passable |
| D. | Very, very poor |
| Answer» A. Poor | |
| 24. |
Hausner Ratio is |
| A. | Tapped density / Bulk density |
| B. | Bulk density / Tapped density |
| C. | bulk volume / void volume |
| D. | void volume / bulk volume |
| Answer» A. Tapped density / Bulk density | |
| 25. |
The powder having low bulk density or large bulk volume is known as |
| A. | Light powder |
| B. | Heavy powder |
| C. | Bulk powder |
| D. | Granular powder |
| Answer» A. Light powder | |
| 26. |
The term Micromeritics was given by |
| A. | J.M. Dalla Valle |
| B. | James Kelvin |
| C. | William Procter |
| D. | Mahadeva Lai Schroff |
| Answer» A. J.M. Dalla Valle | |
| 27. |
Andreasen pipette is widely used method to determine particle size distribution by |
| A. | Microscopy method |
| B. | sedimentation method |
| C. | Sieving method |
| D. | All of the above |
| Answer» B. sedimentation method | |
| 28. |
Porosity is expressed in |
| A. | Percentage |
| B. | Millimeter |
| C. | Gram/Millimeter |
| D. | Newton |
| Answer» A. Percentage | |
| 29. |
Helium Pycnometer is used to determine |
| A. | Size |
| B. | True density |
| C. | Sedimentation rate |
| D. | Surface area |
| Answer» B. True density | |
| 30. |
The porosity of powder is equal to |
| A. | Ratio of void volume to bulk volume. |
| B. | Sum of void volume to bulk volume |
| C. | Product of void volume to bulk volume |
| D. | Void volume only |
| Answer» A. Ratio of void volume to bulk volume. | |
| 31. |
The distance between two tangents on opposite sides of the particle parallel to some fixed direction. |
| A. | Feret's diameter |
| B. | Martin diameter |
| C. | Projected diameter |
| D. | Stoke's diameter |
| Answer» A. Feret's diameter | |
| 32. |
Andreason apparatus consist of |
| A. | Reference electrode |
| B. | Pipette |
| C. | Glass electrode |
| D. | Hydrogen electrode |
| Answer» B. Pipette | |
| 33. |
The physical, chemical, and pharmacologic properties of a drug are directly affected by…… |
| A. | Size |
| B. | Surface area |
| C. | Both of the above |
| D. | None of the above |
| Answer» C. Both of the above | |
| 34. |
............is the science and technology of small particles. |
| A. | Micromeritics |
| B. | Microscopy |
| C. | Rheology |
| D. | None of the above |
| Answer» A. Micromeritics | |
| 35. |
The unit of particle size used is in………… |
| A. | Kilometer (km) |
| B. | Centimeter (Cm) |
| C. | Millimeter (mm) |
| D. | Micrometer (µm) |
| Answer» D. Micrometer (µm) | |
| 36. |
1 micrometer (µm) is equal to |
| A. | 10-5 m |
| B. | 10-6 m |
| C. | 10-7 m |
| D. | 10-8 m |
| Answer» B. 10-6 m | |
| 37. |
Particle size with diameter of 0.5-1.0 Micrometers (µm) is useful for…….. |
| A. | Emulsions |
| B. | Suspensions |
| C. | Both of the above |
| D. | None of the above |
| Answer» C. Both of the above | |
| 38. |
The size of a sphere is freely stated in terms of its............. |
| A. | Area |
| B. | Diameter |
| C. | Radius |
| D. | Volume |
| Answer» B. Diameter | |
| 39. |
…...is the diameter of a sphere having, the same observed area as the particle when viewed normal to its most stable plane. |
| A. | The surface diameter (ds) |
| B. | The projected diameter (dp) |
| C. | The volume diameter (dv) |
| D. | The Stokes diameter (dst) |
| Answer» B. The projected diameter (dp) | |
| 40. |
.... is the number of particles per unit weight. |
| A. | Particle volume |
| B. | Particle number |
| C. | Particle mean |
| D. | Particle weight |
| Answer» B. Particle number | |
| 41. |
…....technique is utilized for estimation of surface diameter ds. |
| A. | Air permeability |
| B. | Vacuum |
| C. | Filtration |
| D. | Weighing |
| Answer» A. Air permeability | |
| 42. |
The ratio of the void volume to the bulk volume of the packing is called as the.................... |
| A. | Tap density |
| B. | Bulk density |
| C. | Followability |
| D. | Porosity |
| Answer» D. Porosity | |
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