McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) , Pharmacy .
Chapters
| 51. |
Which one of the following is not an environmental agent to decrease drug metabolizing ability? |
| A. | DDT |
| B. | Cigarette smoke |
| C. | Organophosphate insecticides |
| D. | Methacholine |
| Answer» D. Methacholine | |
| 52. |
What is polygenic control of drugs? |
| A. | Drug controlling seen in an individual |
| B. | Drug controlling seen in twins |
| C. | Drug controlling seen in between different species |
| D. | Drug controlling seen in a particular population |
| Answer» B. Drug controlling seen in twins | |
| 53. |
Differences observed in metabolism of drug among different races is known as |
| A. | Pharmacogenetics |
| B. | Ethnic variations |
| C. | Discontinues variation |
| D. | Polygenic control |
| Answer» B. Ethnic variations | |
| 54. |
Which age group is known as the neonates? |
| A. | Up to 2 months |
| B. | Up to 2 years |
| C. | Up to 6 months |
| D. | Up to 1 year |
| Answer» A. Up to 2 months | |
| 55. |
Which age group metabolizes drugs faster than the adults? |
| A. | Between 1-12 year |
| B. | Between 1-15 year |
| C. | Between 6-12 year |
| D. | Between 12-18 year |
| Answer» A. Between 1-12 year | |
| 56. |
Fat-free diet depresses cytochrome P-450 level. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» A. True | |
| 57. |
Maternal drug metabolizing ability increases in the later stage of pregnancy. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» B. False | |
| 58. |
Enzyme activity is maximum during the early morning. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» A. True | |
| 59. |
Intermediate of aromatic hydroxylation is |
| A. | Arene |
| B. | Epoxide |
| C. | Aldehyde |
| D. | Ketone |
| Answer» B. Epoxide | |
| 60. |
Oxidation of Propranolol results in |
| A. | 2-hydroxy propranolol |
| B. | 3-hydroxy propranolol |
| C. | 4-hydroxy propranolol |
| D. | 2,2-Dihydroxy propranolol |
| Answer» C. 4-hydroxy propranolol | |
| 61. |
Oxidation of olefin results in |
| A. | Aldehyde |
| B. | Ketone |
| C. | Diol |
| D. | Carboxylic acid |
| Answer» C. Diol | |
| 62. |
Oxidation of Tolbutamide is the example of |
| A. | Oxidation of Olefin |
| B. | Oxidation of Aliphatic carbon |
| C. | Oxidation of Benzylic carbon |
| D. | Oxidation of Allylic carbon |
| Answer» C. Oxidation of Benzylic carbon | |
| 63. |
Carbon atom adjacent to olefinic double bond is known as |
| A. | Alicyclic carbon |
| B. | Aliphatic carbon |
| C. | Benzylic carbon |
| D. | Allylic carbon |
| Answer» D. Allylic carbon | |
| 64. |
Oxidation of Hexobarbital results in |
| A. | 2-hydroxy Hexobarbital |
| B. | 3-hydroxy Hexobarbital |
| C. | 4-hydroxy Hexobarbital |
| D. | 2,3-Dihydroxy Hexobarbital |
| Answer» B. 3-hydroxy Hexobarbital | |
| 65. |
Given reaction is the example of_________ |
| A. | Oxidation of Carbon atom alpha to Carbonyl and Imine |
| B. | Oxidation of Aliphatic carbon |
| C. | Oxidation of Benzylic carbon |
| D. | Oxidation of Allylic carbon |
| Answer» A. Oxidation of Carbon atom alpha to Carbonyl and Imine | |
| 66. |
ω – oxidation of Valproic acid results in |
| A. | 2-hydroxy valproic acid |
| B. | 3-hydroxy valproic acid |
| C. | 4-hydroxy valproic acid |
| D. | 5-hydroxy valproic acid |
| Answer» D. 5-hydroxy valproic acid | |
| 67. |
ω1 – oxidation of Valproic acid results in |
| A. | 2-hydroxy valproic acid |
| B. | 3-hydroxy valproic acid |
| C. | 4-hydroxy valproic acid |
| D. | 5-hydroxy valproic acid |
| Answer» C. 4-hydroxy valproic acid | |
| 68. |
Given reaction is the example of_________ |
| A. | Oxidation of Alicyclic carbon |
| B. | Oxidation of Aliphatic carbon |
| C. | Oxidation of Benzylic carbon |
| D. | Oxidation of Allylic carbon |
| Answer» A. Oxidation of Alicyclic carbon | |
| 69. |
Desulphuration of given drug results in _______ |
| A. | Phenobarbitone |
| B. | Paroxon |
| C. | Sulphanilamide |
| D. | PABA |
| Answer» A. Phenobarbitone | |
| 70. |
Reduction of given drug results in______ |
| A. | Paroxon |
| B. | Sulphanilamide |
| C. | PABA |
| D. | 7 – aminometabolite |
| Answer» D. 7 – aminometabolite | |
| 71. |
Given reaction is the example of ________ |
| A. | Oxidation |
| B. | Reduction |
| C. | Hydrolysis |
| D. | Conjugation |
| Answer» C. Hydrolysis | |
| 72. |
By Glycine conjugation Benzoic acid results in |
| A. | Salicylic acid |
| B. | Oxalic acid |
| C. | Hippuric acid |
| D. | Carbamic acid |
| Answer» C. Hippuric acid | |
| 73. |
The enzymes are divided into two categories, these are _______ and ______ |
| A. | Acidic drug metabolizing and basic drug metabolizing |
| B. | Present in the liver and not present in the liver |
| C. | Microsomal and non-microsomal |
| D. | There is no such division |
| Answer» C. Microsomal and non-microsomal | |
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