McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) , Pharmacy .
Chapters
| 1. |
Aspirin is introduced by_________in 1889 |
| A. | Dreser's |
| B. | Emil Fischer and Mering |
| C. | Barger and Dale |
| D. | None of above |
| Answer» A. Dreser's | |
| 2. |
First hormone epinephrine was synthesized in Year |
| A. | 1903 |
| B. | 1904 |
| C. | 1909 |
| D. | 1889 |
| Answer» B. 1904 | |
| 3. |
Who is founder of modem medicine? |
| A. | Hippocartes |
| B. | Clark |
| C. | Charak |
| D. | Henry's |
| Answer» A. Hippocartes | |
| 4. |
Identification of a new chemical entity as a potential therapeutic agent (From Hit to Lead) is known as |
| A. | Drug discovery |
| B. | Drug development |
| C. | Both of above |
| D. | None of above |
| Answer» A. Drug discovery | |
| 5. |
The process of bringing a new pharmaceutical drug to the market once the lead compound has been identified through the process of drug discovery. (From Lead to NDA) is known as |
| A. | Drug discovery |
| B. | Drug development |
| C. | Both of above |
| D. | None of above |
| Answer» B. Drug development | |
| 6. |
Natural products or derivatives or synthetic substances with good binding ability in Drug discovery is known as |
| A. | Hit |
| B. | Lead |
| C. | NDA |
| D. | IND |
| Answer» A. Hit | |
| 7. |
Compound with good activity and selectivity in screening during drug discovery is known as |
| A. | Hit |
| B. | Lead |
| C. | NDA |
| D. | IND |
| Answer» B. Lead | |
| 8. |
The main goals of pre-clinical studies |
| A. | To determine the safe dose for first-in-man study |
| B. | To assess a product's safety profile |
| C. | A and B both |
| D. | None |
| Answer» C. A and B both | |
| 9. |
IND stands for |
| A. | Improved new drug |
| B. | Investigational new drug |
| C. | International new drug |
| D. | International novel drug |
| Answer» B. Investigational new drug | |
| 10. |
Human micro dosing studies conducted in which clinical phase ? |
| A. | Phase 0 |
| B. | Phase I |
| C. | Phase II |
| D. | Phase III |
| Answer» A. Phase 0 | |
| 11. |
MTD is |
| A. | Maximum targeted dose |
| B. | Minimum tolerated dose |
| C. | Minimum targeted dose |
| D. | Maximum tolerated dose |
| Answer» D. Maximum tolerated dose | |
| 12. |
Single ascending dose studies are done in_____ |
| A. | Phase lb |
| B. | Phase Ia |
| C. | Phase II |
| D. | Phase Ila |
| Answer» B. Phase Ia | |
| 13. |
NDA is |
| A. | New Drug Application |
| B. | New Drug approval |
| C. | Noval Drug Admistration |
| D. | New Drug agenda |
| Answer» A. New Drug Application | |
| 14. |
Phase IV trial is also known |
| A. | Base of clinical trial |
| B. | Multiple ascending dose era |
| C. | Post marketing Surveillance |
| D. | Pre-clinical trial |
| Answer» C. Post marketing Surveillance | |
| 15. |
How many people will be selected for phase I trial? |
| A. | The whole market will be under surveillance |
| B. | 300-3000 people |
| C. | 20-300 people |
| D. | 20-50 people |
| Answer» D. 20-50 people | |
| 16. |
How many people will be selected for phase II trial? |
| A. | The whole market will be under surveillance |
| B. | 300-3000 people |
| C. | 20-300 people |
| D. | 20-50 people |
| Answer» C. 20-300 people | |
| 17. |
How many people will be selected for phase III trial? |
| A. | The whole market will be under surveillance |
| B. | 300-3000 people |
| C. | 20-300 people |
| D. | 20-50 people |
| Answer» B. 300-3000 people | |
| 18. |
Which one of the following will be checked under phase IV surveillance? |
| A. | The whole market will be under surveillance |
| B. | 300-3000 people |
| C. | 20-300 people |
| D. | 20-50 people |
| Answer» A. The whole market will be under surveillance | |
| 19. |
Precision Medicine is an emerging approach depending on |
| A. | Genomic study of individual |
| B. | Diagnostic process of individual |
| C. | Diseases conditions |
| D. | None of above |
| Answer» A. Genomic study of individual | |
| 20. |
How many main families of GPCRs are there? |
| A. | 5 |
| B. | 6 |
| C. | 7 |
| D. | 4 |
| Answer» B. 6 | |
| 21. |
Which of the following reactions is catalyzed by the enzyme adenylate cyclase? |
| A. | Conversion of ATP to cyclic AMP |
| B. | Conversion of cyclic AMP to AMP |
| C. | Conversion of cyclic AMP to ATP |
| D. | Conversion of AMP to cyclic AMP |
| Answer» A. Conversion of ATP to cyclic AMP | |
| 22. |
Oxadiazole ring contains |
| A. | 1 Nitrogen /Oxygen |
| B. | 2 Oxygen/ Nitrogen |
| C. | 2 Nitrogen/Sulphur |
| D. | 2 Nitrogen/Oxygen |
| Answer» D. 2 Nitrogen/Oxygen | |
| 23. |
The hetroaromatic redical is called |
| A. | Anthryl |
| B. | Naphthyl |
| C. | Phenanthryl |
| D. | Dibenzyl |
| Answer» B. Naphthyl | |
| 24. |
Name of this aromatic ring is |
| A. | Diphenylmethyl ethane |
| B. | 2-ethyl-1-methyl naphthalene |
| C. | 1-ethyl-2-methyl naphthalene |
| D. | 1-ethyl-1-methyl naphthalene |
| Answer» C. 1-ethyl-2-methyl naphthalene | |
| 25. |
Name of this aromatic ring is |
| A. | Azopane |
| B. | Azepine |
| C. | Azepane |
| D. | None of above |
| Answer» C. Azepane | |
| 26. |
Which of the following statements best describes pharmacodynamics? |
| A. | The study of how drugs reach their target in the body and how the levels of a drug in the blood are affected by absorption, distribution, metabolism and excretion. |
| B. | The study of how drugs can be designed using molecular modelling based on a drug's pharmacophore. |
| C. | The study of how a drug interacts with its target binding site at the molecular level. |
| D. | The study of which functional groups are important in binding a drug to its target binding site and the identification of a pharmacophore. |
| Answer» C. The study of how a drug interacts with its target binding site at the molecular level. | |
| 27. |
Which of the following statements best describes pharmacokinetics? |
| A. | The study of how drugs reach their target in the body and how the levels of a drug in the blood are affected by various factors. |
| B. | The study of how drugs can be designed using molecular modelling based on a drug's pharmacophore. |
| C. | The study of how a drug interacts with its target binding site at the molecular level. |
| D. | The study of which functional groups are important in binding a drug to its target binding site and the identification of a pharmacophore. |
| Answer» A. The study of how drugs reach their target in the body and how the levels of a drug in the blood are affected by various factors. | |
| 28. |
What are soft drugs? |
| A. | Drugs given to babies |
| B. | Chemical drugs which are already found in the body |
| C. | Nutrients which kill the gut harmful microbes |
| D. | Anything that is not nutrients and enters the body through different routes |
| Answer» B. Chemical drugs which are already found in the body | |
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