McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Biology .
Chapters
| 1. |
Regarding equilibrium potential (mammalian spinal motor neurons) |
| A. | The resting membrane potential is – 70 mV – identical to that of Ecl |
| B. | Equilibrium potential of potassium is +90 mV |
| C. | Increases in external sodium concentrations decrease the resting membrane potential |
| D. | Equilibrium potential of sodium is –60 mV |
| E. | Na+K+ ATPase pumps 2 sodium out of cell for every 3 potassium it pumps in |
| Answer» A. The resting membrane potential is – 70 mV – identical to that of Ecl | |
| 2. |
Regarding body composition |
| A. | 18% body weight is protein / related substances |
| B. | 15% body weight is interstitial fluid |
| C. | 60% body weight is water |
| D. | 5% body weight is plasma |
| E. | All of the above are true |
| Answer» E. All of the above are true | |
| 3. |
Regarding buffers in the body |
| A. | Initial correction of pH disturbance is achieved by the kidneys |
| B. | The phosphate buffer system is the predominant buffer in the blood |
| C. | Bones contribute to buffering by taking up bicarbonate |
| D. | Hb is an important buffer in the blood |
| E. | All of the above are true |
| Answer» D. Hb is an important buffer in the blood | |
| 4. |
The size of the action potential is decreased by |
| A. | Decreased extracellular calcium |
| B. | Increased external sodium |
| C. | Decreased internal sodium |
| D. | Decreased internal potassium |
| E. | Increased internal potassium |
| Answer» C. Decreased internal sodium | |
| 5. |
Regarding body fluid compartments |
| A. | About 2/3 TBW is extracellular |
| B. | ECF / intracellular fluid volume ratio is larger in infants than in adults |
| C. | Plasma volume in a 70 kg male is approximately 5 litres |
| D. | A 30 year old male has 40% water as a percentage of body weight |
| E. | Transcellular fluid has a greater volume than intracellular fluids |
| Answer» B. ECF / intracellular fluid volume ratio is larger in infants than in adults | |
| 6. |
Fick’s Law of Diffusion is dependent on all EXCEPT |
| A. | The posture of the subject |
| B. | The solubility of the gas |
| C. | Thickness of membrane barrier |
| D. | Molecular weight of the gas |
| E. | Area of the membrane |
| Answer» A. The posture of the subject | |
| 7. |
Regarding movement across cell membranes |
| A. | Exocytosis requires sodium and energy |
| B. | Insulin reuptake is by receptor mediated endocytosis |
| C. | Thyroid hormones decrease the activity of the NaK ATPase |
| D. | Active transport of sodium is rarely coupled with other substances |
| E. | NaK ATPase has a 1:1 coupling ratio |
| Answer» B. Insulin reuptake is by receptor mediated endocytosis | |
| 8. |
In regard to pH |
| A. | pH of a solution is the log to base 10 of the reciprocal hydrogen ion concentration |
| B. | Is the negative log of the concentration of hydrogen ions |
| C. | For each pH unit less than 7 – the concentration of hydrogen ion is increased 10 fold |
| D. | A pH of 7 is equal to a hydrogen ion concentration of 10-7 mmol/l |
| E. | All of the above are true |
| Answer» E. All of the above are true | |
| 9. |
Regarding heterotrimeric G proteins |
| A. | GDP is bound to the B subunit |
| B. | They are not serpentine receptors |
| C. | The delta unit separates from the other subunits to bring about the biological effect |
| D. | The intrinsic GTPase activity of the alpha subunit converts GTP to GDP |
| E. | They span the membrane seven times |
| Answer» E. They span the membrane seven times | |
| 10. |
Which of the following is correct? |
| A. | Chloride concentration in interstitial fluid is greater than in the plasma |
| B. | Potassium concentration in interstitial fluid is greater than that in intracellular fluid |
| C. | Sodium concentration in intracellular fluid is greater than in plasma |
| D. | Protein concentration in plasma is greater than in intracellular fluid |
| E. | Bicarbonate concentration in intracellular fluid is greater than in interstitial fluid |
| Answer» A. Chloride concentration in interstitial fluid is greater than in the plasma | |
| 11. |
Regarding basic physiological measures – all of the following are true EXCEPT |
| A. | Osmolarity is the number of osmoles / litre of solution |
| B. | PH is the log to base 10 of the reciprocal of hydrogen ion concentration |
| C. | Carbon has a molecular mass of 12 dalton |
| D. | Osmolarity is measured by freezing point depression |
| E. | One equivalent of sodium is 23 g/l |
| Answer» D. Osmolarity is measured by freezing point depression | |
| 12. |
With regards to cell membrane potential |
| A. | The Donnan effect relies on nondiffusible ions |
| B. | The exterior of the cell is negative with respect to the interior |
| C. | The membrane potential tends to push chloride out of the cell |
| D. | It can be derived by measuring the chloride concentration and using the Nernst equation |
| E. | Potassium leaks out against its concentration gradient |
| Answer» A. The Donnan effect relies on nondiffusible ions | |
| 13. |
Regarding the comparison of ECF with CSF – all of the following are true EXCEPT |
| A. | CSF has less protein |
| B. | CSF has lower osmolality |
| C. | CSF has lower pH |
| D. | CSF has more bicarbonate |
| E. | CSF has lower specific gravity |
| Answer» B. CSF has lower osmolality | |
| 14. |
Which of the following does NOT act via an intracellular receptor? |
| A. | Cortisol |
| B. | Thyroxine |
| C. | ANP |
| D. | Aldosterone |
| E. | Retinoic acid |
| Answer» C. ANP | |
| 15. |
Regarding functional morphology of the cell |
| A. | Tay Sachs disease is a cell membrane disorder |
| B. | Actin is the most abundant protein in mammalian cells |
| C. | Peroxisomes are 5 um in diameter |
| D. | The assembly of microtubules in the cell cytoskeleton is facilitated by cold |
| E. | Myosin 1 is present in skeletal muscle |
| Answer» B. Actin is the most abundant protein in mammalian cells | |
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