After total proctocolectomy with ileal pouch anal anastomoses what is the most common cause of death in patients with Familial Adenomatous Polyposis (FAP)

Related MCQs

• Which of the following is not true for malignancy of Familial Adenomatous Polyposis
• Familial polyposis coli
• A 76-year-old male was admitted for symptoms including constipation, change in stool character and weight loss. Colonoscopy revealed multiple polyps in the rectosigmoid area. An adenomatous polyp was removed. Another colonic tumor was seen in the same patient which was flat with irregular “shaggy rug” surface. A biopsy showed frond-like glandular architecture. Atypical epithelial cells in clusters were seen beneath the muscularis mucosae. The most likely diagnosis is:
• For previous patients, after the appropriate evaluation, the patient undergoes surgery. No intraoperative evidence of metastases is identified. Postoperatively, the pathology report reveals that the tumor is an adenocarcinoma invading into the pericolonic fat, with 2 involved lymph nodes. After the patient recovers from surgery, which of the following is the most appropriate next step in his management?
• Which of the following studies compared surgery alone versus surgery plus external-beam pelvic irradiation in patients with early-stage endometrial cancer and required all patients to undergo surgical staging with pelvic lymphadenectomy?
• The genetic defect in hereditary non-polyposis coli lies in:
• A 45 years old female with right sided breast cancer with no family history suggesting familial cancer. The most likely genetic mutation for this patient is/are
• Risk of Malignancy in Adenomatous polyp is related to all except
• Concerning adenomatous polyps, all the following are true EXCEPT:
• A 34-year-old woman is evaluated because of progressive fatigue and recurrent attacks of abdominal pain. She weighs 61.2 kg (135 Ib). Her pulse rate is 110/min and her blood pressure is 110/70 mm Hg. She is pale, and her spleen is palpable 4 cm below the costal margin. Laboratory studies: Hemoglobin 6 g/dL Hematocrit 20% Leukocyte count 2500/μL Platelet count 80,000/μL Reticulocyte count 10% Blood smear Anisocytosis and polychromatophilia Haptoglobin 0 mg/dL Serum lactate dehydrogenase 645 U/L There is high level of hemosiderin in the urine. What is the most likely cause of this patients pancytopenia?