McqMate
| 1. |
Hard gelatin capsule contains ______% of moisture |
| A. | 13-16% |
| B. | 13.5-16% |
| C. | 12-16% |
| D. | 12-15% |
| Answer» A. 13-16% | |
| 2. |
Protien constituent of gelatin is type of amino acid |
| A. | essential amino acid |
| B. | non essential amino acid |
| C. | glycine & proline |
| D. | both b&c |
| Answer» D. both b&c | |
| 3. |
Nanocapsules have size less than |
| A. | 1-20um |
| B. | 1-50um |
| C. | 20-50um |
| D. | 1-30um |
| Answer» A. 1-20um | |
| 4. |
Official anhydrous water miscible ointment bases i.e emulsifying ointment contains |
| A. | cationic emulsifier |
| B. | nonionic emulsifier |
| C. | anionic emulsifier |
| D. | none of above |
| Answer» C. anionic emulsifier | |
| 5. |
Polyethylene glycol is also called as |
| A. | macrogols |
| B. | carbowaxes |
| C. | both a&b |
| D. | cetogols |
| Answer» C. both a&b | |
| 6. |
What is bloom strength of hard gelatin shell. |
| A. | 150 g |
| B. | 220-280 g |
| C. | 170 g |
| D. | 190 g |
| Answer» B. 220-280 g | |
| 7. |
Source of rae material derived from cown can be gelatin |
| A. | bone |
| B. | hide |
| C. | skin |
| D. | both a&b |
| Answer» D. both a&b | |
| 8. |
The largest size of capsule is |
| A. | 5 |
| B. | 8 |
| C. | 0 |
| D. | 0 |
| Answer» D. 0 | |
| 9. |
Obaka automatic capsule filler capable of filling up to_____capsule/hour |
| A. | 1000 |
| B. | 200 |
| C. | 165000 |
| D. | 200-1000 |
| Answer» C. 165000 | |
| 10. |
Hazing of the film is also called as |
| A. | dull film |
| B. | bloom |
| C. | arrange peel effect |
| D. | botha&c |
| Answer» D. botha&c | |
| 11. |
Spanules are |
| A. | soft gelatin capsule |
| B. | hard gelatin capsule |
| C. | hard gelatin capsule filled with coated granules or bed |
| D. | bothb&c |
| Answer» C. hard gelatin capsule filled with coated granules or bed | |
| 12. |
Nanocapsules have size less than |
| A. | 1-20um |
| B. | 1-50um |
| C. | 20-50um |
| D. | 1-30um |
| Answer» A. 1-20um | |
| 13. |
the first digit in the propellent number represent |
| A. | no, of fluorin atom |
| B. | no.of carbon atom |
| C. | no, of hydrogen atom |
| D. | none of above |
| Answer» B. no.of carbon atom | |
| 14. |
The Exveka KEA is |
| A. | dedusting & polishing machine of tablet |
| B. | dedusting of tablet |
| C. | polishing machine of capsule |
| D. | dedusting and polishing machine of capsule |
| Answer» D. dedusting and polishing machine of capsule | |
| 15. |
____element in regularly given to modify the solubility of gelatin capsule |
| A. | additive |
| B. | formaline |
| C. | water |
| D. | formaline and water |
| Answer» B. formaline | |
| 16. |
Isoelectric point of type A gelatin is______ |
| A. | 4.8-5 |
| B. | 5-5.8 |
| C. | 7_9 |
| D. | 4_6 |
| Answer» A. 4.8-5 | |
| 17. |
7-9 is isoelectric point of |
| A. | gelatin |
| B. | type b |
| C. | type c |
| D. | both b & c |
| Answer» B. type b | |
| 18. |
Dip coating is use for |
| A. | repeated coating and dying |
| B. | acid insoluble coating |
| C. | botha & c |
| D. | none of above |
| Answer» B. acid insoluble coating | |
| 19. |
Relative humidity of softgel is |
| A. | 0.35 |
| B. | 0.2 |
| C. | 0.15 |
| D. | 20-25% |
| Answer» A. 0.35 | |
| 20. |
Tag open cap apparatus for evalution of |
| A. | flame projection |
| B. | identification of propellent |
| C. | flash point |
| D. | aerosole value discharge rate |
| Answer» C. flash point | |
| 21. |
Aerosole store at temperature above |
| A. | 40 c |
| B. | 49 c |
| C. | 25 c |
| D. | 37 c |
| Answer» A. 40 c | |
| 22. |
Dip tubes in aerosols are made up of______ |
| A. | polyethylene & polypropylene |
| B. | polyarcryne |
| C. | polyarcryne & polyethylene |
| D. | none of above |
| Answer» A. polyethylene & polypropylene | |
| 23. |
Which one of the following comes under the category of oleaginous bases |
| A. | wool fat |
| B. | liq.paraffin |
| C. | hydrous wool fat |
| D. | bees wax |
| Answer» B. liq.paraffin | |
| 24. |
Hydrous wool fat is a mixture of |
| A. | 70%w/w wool fat&30%w/w purified water |
| B. | 60%w/w wool fat&40%w/w purified water |
| C. | 30%w/w wool fat&70%w/w purified water |
| D. | 80%w/w wool fat&20%w/w purified water |
| Answer» A. 70%w/w wool fat&30%w/w purified water | |
| 25. |
Polyethylene glycol is also called as |
| A. | macrogols |
| B. | carbowaxes |
| C. | both a&b |
| D. | cetogols |
| Answer» C. both a&b | |
| 26. |
Which of the following is viscous liquid |
| A. | macrogel 1500 |
| B. | macrogel 400 |
| C. | macrogel 1540 |
| D. | macrogel 6000 |
| Answer» B. macrogel 400 | |
| 27. |
Simple ointment contains base |
| A. | oleaginous |
| B. | water soluble |
| C. | water immiscible |
| D. | none of above |
| Answer» A. oleaginous | |
| 28. |
Liquid paraffin IP has viscosity greater than |
| A. | 65 centistokes |
| B. | 60 centistokes |
| C. | 30 centistokes |
| D. | all of the above |
| Answer» D. all of the above | |
| 29. |
Tragacanth has HLB value |
| A. | 9.8 |
| B. | 9.7 |
| C. | 12.01 |
| D. | 13.2 |
| Answer» D. 13.2 | |
| 30. |
Sudden increase in solubility of micells forming surfactant above definite tempreture is known as |
| A. | cloud point |
| B. | kraft point |
| C. | cmc |
| D. | none of above |
| Answer» B. kraft point | |
| 31. |
Polysorbate 20 inactivates |
| A. | parabens |
| B. | mercurials |
| C. | benzalconium chloride |
| D. | thiazole |
| Answer» C. benzalconium chloride | |
| 32. |
Liquid paraffin shows type of flow |
| A. | plastic |
| B. | newtonian flow |
| C. | pseudoplastic |
| D. | thixotropic |
| Answer» C. pseudoplastic | |
| 33. |
Protective property of colloid is expressed by |
| A. | gold no. |
| B. | silver no. |
| C. | botha&b |
| D. | none of above |
| Answer» A. gold no. | |
| 34. |
Unna’s paste is mixture of |
| A. | ferric oxide,saccharine,sodium & gelatin |
| B. | ferric oxide,glycerin&gelatin |
| C. | zinc oxide,ferric oxide |
| D. | zinc oxide,glycerine & gelatin |
| Answer» D. zinc oxide,glycerine & gelatin | |
| 35. |
Conductivity test is performed for |
| A. | w/o emulsion system |
| B. | o/w emulsion system |
| C. | o/w/o emulsion system |
| D. | dispersed system |
| Answer» B. o/w emulsion system | |
| 36. |
Bottle method preparation of emulsion used the proportion of fixed oil:water:acacia |
| A. | 0.0847337962962963 |
| B. | 0.04238425925925926 |
| C. | 0.08403935185185185 |
| D. | 0.04306712962962963 |
| Answer» C. 0.08403935185185185 | |
| 37. |
______ is the bactericidal recommended for ophthalmic used |
| A. | parabens |
| B. | phenyl mercuric citrate |
| C. | chlorocresol |
| D. | benzalconium chloride |
| Answer» D. benzalconium chloride | |
| 38. |
The output of a typical rotary machine ranges from --to—suppositories an hour |
| A. | 3500-6000 |
| B. | 6000-6500 |
| C. | 3000-6000 |
| D. | 6500-7500 |
| Answer» A. 3500-6000 | |
| 39. |
The displacement factor of boric acid is ____to the cocoa butter |
| A. | 0.81 |
| B. | 0.61 |
| C. | 0.83 |
| D. | 0.67 |
| Answer» D. 0.67 | |
| 40. |
Cocoa butter suppositories in storage sometime form |
| A. | a white powder diposite on surface |
| B. | liquefied |
| C. | melt of suppository |
| D. | both b&c |
| Answer» A. a white powder diposite on surface | |
| 41. |
The suppositories should be stored at |
| A. | 25+20c & 40c |
| B. | 25+30c & 40c |
| C. | 25+50c & 40c |
| D. | 25+0.250c & 40c |
| Answer» B. 25+30c & 40c | |
| 42. |
Melting point of suppositories base is determined by |
| A. | incipient/thaw point |
| B. | wiley melting point |
| C. | both a&b |
| D. | none og above |
| Answer» D. none og above | |
| 43. |
The gamma form of cocoa butter melts at |
| A. | 190 c |
| B. | 170 c |
| C. | 180 c |
| D. | all of the above |
| Answer» D. all of the above | |
| 44. |
The melting point of cocoa butter lies between__to__ |
| A. | 86-95f |
| B. | 86-96f |
| C. | 96-100f |
| D. | 87-90f |
| Answer» A. 86-95f | |
| 45. |
Formula for HLB value is |
| A. | 20-[1-acid value/sap value] |
| B. | 20-[1-sap value/acid value] |
| C. | 40-[1-sap value/displacement value] |
| D. | all of above |
| Answer» D. all of above | |
| 46. |
Polyethylene glycol bases are incompatible with |
| A. | sodium salt |
| B. | tannic acid |
| C. | silver salts |
| D. | both a&c |
| Answer» D. both a&c | |
| 47. |
Maillard reaction asociated with |
| A. | diluents |
| B. | binder |
| C. | lubricant |
| D. | adherent |
| Answer» A. diluents | |
| 48. |
Which is the foolowing ingredient use as antiadherent |
| A. | acrosil |
| B. | mcc |
| C. | hpmc |
| D. | vegum |
| Answer» A. acrosil | |
| 49. |
Its shows negative heat of solution are |
| A. | manitol |
| B. | sorbitol |
| C. | dextrose |
| D. | sucrose |
| Answer» A. manitol | |
| 50. |
Trade name of microcrystalline cellulose is |
| A. | avicel |
| B. | cab-o-sil |
| C. | erodex |
| D. | celutab |
| Answer» A. avicel | |
| 51. |
Lubricant used in tablet formulation for |
| A. | to lubricate all ingredient in the tablet |
| B. | prevent adhesion of tablet material to surface area of dies |
| C. | reduce interparticle friction,improve rate of flow |
| D. | both a&b |
| Answer» D. both a&b | |
| 52. |
Which of the superdisintegrants are used in tablet formulation |
| A. | croscarmelose |
| B. | crospovidone |
| C. | both a&b |
| D. | none of above |
| Answer» C. both a&b | |
| 53. |
Thinner the tablet indicates that |
| A. | hard tablet |
| B. | size is less |
| C. | soft tablet |
| D. | none of above |
| Answer» A. hard tablet | |
| 54. |
Which of the following material used in enteric coated tablet |
| A. | cap |
| B. | hpmc |
| C. | mcc |
| D. | hpc |
| Answer» A. cap | |
| 55. |
Which is the following modified starch |
| A. | starx-1500 |
| B. | rx-500 |
| C. | both a&b |
| D. | none of above |
| Answer» A. starx-1500 | |
| 56. |
Which are the following apparatus used for tablet hardnes testing |
| A. | monsanto |
| B. | strong cob |
| C. | roache |
| D. | both a&b |
| Answer» A. monsanto | |
| 57. |
Unit of hardness |
| A. | kg/sq.in |
| B. | kg/sq.foot |
| C. | mg/sq.cm |
| D. | kg/sq.cm |
| Answer» D. kg/sq.cm | |
| 58. |
According to USP type I dissolution apparatus is |
| A. | basket |
| B. | paddle |
| C. | basket and paddle |
| D. | none of above |
| Answer» A. basket | |
| 59. |
Which are the following apparatus used for friability testing |
| A. | roache fribilator |
| B. | pfizer |
| C. | orasaka fribilator |
| D. | none of above |
| Answer» A. roache fribilator | |
| 60. |
According to USP standard limit for friability test is |
| A. | 0.5-1% |
| B. | 0.4-1% |
| C. | 0.8-1.2% |
| D. | 0.1-1% |
| Answer» A. 0.5-1% | |
| 61. |
According to IP disintegration time for dispersible tablet is |
| A. | within 3 min in water at 250c + 10c |
| B. | within 2 min in water at 250c+10c |
| C. | within 1 min in water at 270c |
| D. | none of above |
| Answer» A. within 3 min in water at 250c + 10c | |
| 62. |
According to std sparingly soluble means |
| A. | less than 1 part of solvent required for 1 part of solute |
| B. | from 10-30 parts of solvent required for 1 part of solute |
| C. | from 1000 to 10000 parts of solvent required for 1 part of solute |
| D. | from 100 to 1000 parts of solvent required for 1 part of solute |
| Answer» A. less than 1 part of solvent required for 1 part of solute | |
| 63. |
Seperation of tablet into two or more distinct layer |
| A. | capping |
| B. | lamination |
| C. | shipping |
| D. | both a&b |
| Answer» B. lamination | |
| 64. |
Unequal distribution of colour on a tablet with dark spot is |
| A. | mottling |
| B. | colour variation |
| C. | orange peel effect |
| D. | both a & b |
| Answer» D. both a & b | |
| 65. |
Chipping is the tablet defect in |
| A. | breaking of tablet edges |
| B. | crack of tablet surface |
| C. | adhering tablet to die wall |
| D. | stick of tablet |
| Answer» A. breaking of tablet edges | |
| 66. |
Which of the following is principal area of preformulation |
| A. | bulk characterization |
| B. | solubility analysis |
| C. | stability analysis |
| D. | all of above |
| Answer» A. bulk characterization | |
| 67. |
Which are the form are more stable |
| A. | crystalline |
| B. | amorphous |
| C. | polymorphs |
| D. | entiotrops |
| Answer» D. entiotrops | |
| 68. |
Which of the following form having less solubility and lesser tendency to change its form during storage |
| A. | amorphous form |
| B. | crystalline |
| C. | botha&b |
| D. | none of above |
| Answer» A. amorphous form | |
| 69. |
Metastable form having tendency to convert into |
| A. | stable form |
| B. | unstable form |
| C. | amorphous form |
| D. | none of above |
| Answer» B. unstable form | |
| 70. |
Deliquesent materials means |
| A. | they absorb sufficient amount of moisture b) they absorb moisture |
| B. | they absorb moisture |
| C. | they losses the water |
| D. | none of the above |
| Answer» A. they absorb sufficient amount of moisture b) they absorb moisture | |
| 71. |
Which of the following method used for amount of moisture absorb determination |
| A. | gravimetry |
| B. | tga |
| C. | karl-fischer titration |
| D. | all of the above |
| Answer» A. gravimetry | |
| 72. |
Which of the following ingredient or polymer used in enteric coated tablet and for purpose of are |
| A. | cap(cellulose acetate phthalate ) |
| B. | mcc for resistant to acidic ph |
| C. | for resistant to acidic ph |
| D. | none of the above |
| Answer» C. for resistant to acidic ph | |
| 73. |
Controlled drug delivery system recently been marketed as |
| A. | rate-preprogrammed drug delivery system |
| B. | activation-modulated drug delivery system |
| C. | site-targeting drug delivery system |
| D. | all of the above |
| Answer» D. all of the above | |
| 74. |
Various types of polymer membrane permeation-controlled drug delivery systems includes |
| A. | sphere |
| B. | cylinder |
| C. | sheet |
| D. | all of the above |
| Answer» D. all of the above | |
| 75. |
Following parameters play varying degrees of rate-limiting roles in controlling the release of drug molecules from membrane permeation or matrix diffusion |
| A. | partition coefficient |
| B. | diffusional path thickness |
| C. | solubility |
| D. | all of the above |
| Answer» D. all of the above | |
| 76. |
The diffusion of small molecules in a polymer structure is an |
| A. | energy-activated process |
| B. | increase in concentration |
| C. | increase in no of small molecules |
| D. | all of the above |
| Answer» A. energy-activated process | |
| 77. |
The controlled release of a drug species from both polymer membrane and polymer matrix controlled drug delivery systems is governed by |
| A. | ???? fick’s law of diffusion |
| B. | ???? arrhenius relationship |
| C. | ???? both a & b |
| D. | ?? none of the above |
| Answer» A. ???? fick’s law of diffusion | |
| 78. |
In establishing a good in vitro & in vivo correlation of CDDS following should consider |
| A. | pharmaceutics aspects of controlled release drug delivery systems |
| B. | bio-pharmaceutics and pharmacokinetics of the therapeutic agent in the body after its delivery from a drug delivery systems |
| C. | pharmacodynamics of the therapeutic agent at the site of drug actions |
| D. | all of the above |
| Answer» D. all of the above | |
| 79. |
Solubilization of poorly soluble drugs in aqueous solution can be effectively accomplished by using |
| A. | co-solvent systems |
| B. | increase in the concentration of drugs |
| C. | both a & b |
| D. | none of the above |
| Answer» A. co-solvent systems | |
| 80. |
The effect of partition coefficient on the controlled release of drugs from a matrix type drug delivery device was reported as |
| A. | the mechanism of drug release were dependent upon the variation in the partition coefficient |
| B. | the rate profile of drug release were dependent upon the variation in the partition coefficient |
| C. | both a & b |
| D. | none of the above |
| Answer» C. both a & b | |
| 81. |
Fillers are often incorporated into polymer to enhance |
| A. | kinetic strength |
| B. | mechanical strength |
| C. | none of the above |
| D. | both a & b |
| Answer» B. mechanical strength | |
| 82. |
Both the in-vitro and in-vivo rates of drug release are observed to be dependent on |
| A. | upon the surface area of drug delivery device |
| B. | different lengths of treatment |
| C. | both a & b |
| D. | none of the above |
| Answer» C. both a & b | |
| 83. |
One of the materials listed below is most commonly used in film coating of Tablets, Identify. |
| A. | (a) hydroxypropyl methyl cellulose |
| B. | (b) acacia |
| C. | (c) simple syrup |
| D. | (d) bees wax |
| Answer» A. (a) hydroxypropyl methyl cellulose | |
| 84. |
The loading dose of a drug is usually based on |
| A. | (a) total body clearance of the drug |
| B. | (b) percentage of drug bound to plasma proteins |
| C. | (c) fraction of drug excreted unchanged in urine |
| D. | (d) apparent volume of distribution and desired drug concentration in plasma |
| Answer» D. (d) apparent volume of distribution and desired drug concentration in plasma | |
| 85. |
The characteristics of a good NDDS carrier are: |
| A. | (a) optimum drug quantity can be loaded into it. |
| B. | (b) the release of the drug inside the body is pulsatile in nature. |
| C. | (c) it should not be immunogenic in nature. |
| D. | (d) all of the above |
| Answer» D. (d) all of the above | |
| 86. |
Tablet is one of the following forms that an oral drug can take such as |
| A. | (a)?????? syrups & suspension |
| B. | (b)???? elixirs & emulsion |
| C. | (c)?????? both a & b |
| D. | (d)???? none of the above |
| Answer» C. (c)?????? both a & b | |
| 87. |
A wide variety of binders used in tablet dosage form some common one including |
| A. | (a) dibasic calcium phosphate |
| B. | (b) corn (maize) starch |
| C. | (c ) povidone polyvinylpyrrolidone and modified cellulose |
| D. | (d)?????????? all of the above |
| Answer» D. (d)?????????? all of the above | |
| 88. |
The hardness of tablets is the principle measurement of |
| A. | (a) mechanical strength |
| B. | (b) kinetic energy |
| C. | (c ) both a & b |
| D. | (a)?????? none of the above |
| Answer» A. (a) mechanical strength | |
| 89. |
Capsules are made from aqueous solutions of gelling agents like |
| A. | (a) animal protein mainly gelatin |
| B. | (b) plant polysaccharides |
| C. | (c ) modified forms of starch and cellulose |
| D. | (d) all the above |
| Answer» D. (d) all the above | |
| 90. |
Vegetable capsules are composed of |
| A. | (a) hypromellose |
| B. | (b) a polymer formulated from cellulose |
| C. | (c) both a & b |
| D. | (d) none of the above |
| Answer» C. (c) both a & b | |
| 91. |
The applicability of Noyes-Whitney equation is to describe |
| A. | (a) first order kinetics???????????? |
| B. | (b) zero order kinetics |
| C. | (c) mixed order kinetics?????? |
| D. | (d) dissolution rate |
| Answer» D. (d) dissolution rate | |
| 92. |
The ability of human eye using illuminated area to detect a particle is limited to |
| A. | (a) 0.4 micron???????? |
| B. | (b) 25 micron???????? |
| C. | (c) 50 micron???????? |
| D. | (d) 10 micron |
| Answer» D. (d) 10 micron | |
| 93. |
Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid discoloration of the tablets? |
| A. | (a) dicalcium phosphate?????????? |
| B. | (b) microcrystalline cellulose |
| C. | (c) starch?????????????????? ???????????????????????? ???? ?? |
| D. | (d) lactose |
| Answer» D. (d) lactose | |
| 94. |
In which of the following techniques the sample is kept below triple point? |
| A. | (a) lyophilization???????????????????? ?? |
| B. | (b) spray drying |
| C. | (c) spray congealing?????????????? ?? |
| D. | (d) centrifugation |
| Answer» A. (a) lyophilization???????????????????? ?? | |
| 95. |
Drugs in suspensions and semi-solid formulations always degrade by |
| A. | (a) first order kinetics???????????????? |
| B. | (b) second order kinetics |
| C. | (c) zero order kinetics???????????????? |
| D. | (d) non-linear kinetics |
| Answer» C. (c) zero order kinetics???????????????? | |
| 96. |
Modified release drug delivery systems may be divided conveniently in to following categories |
| A. | (a) delayed release & sustained release |
| B. | (b) site specific targeting & receptor targeting |
| C. | (c) both a & b |
| D. | (d) none of the above |
| Answer» C. (c) both a & b | |
| 97. |
According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed? |
| A. | (a)???? 1%?????? |
| B. | (b)???? 2%?????? |
| C. | (c)???? 4%?????? |
| D. | (d)???? 5% |
| Answer» A. (a)???? 1%?????? | |
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