McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) .
Chapters
| 51. |
What will be the renal clearance if the rate of urinary excretion is 625 ml/min and plasma drug concentration is 4.2 ng/ml? |
| A. | 148.80ml2/ng min |
| B. | 150ml2/ng min |
| C. | 152ml2/ng min |
| D. | 140ml2/ng min |
| Answer» A. 148.80ml2/ng min | |
| 52. |
How renal clearance ratio is expressed? |
| A. | Renal clearance of creatinine / renal clearance of the drug |
| B. | 1/renal clearance of the drug |
| C. | Renal clearance of drug/ renal clearance of creatinine |
| D. | 1/renal clearance of creatinine |
| Answer» C. Renal clearance of drug/ renal clearance of creatinine | |
| 53. |
What will be the renal clearance ratio of a drug whose renal clearance is 40ml/min and the clearance of creatinine is 95ml/min? |
| A. | 0.421 |
| B. | 2.38 |
| C. | 0.010 |
| D. | 0.025 |
| Answer» A. 0.421 | |
| 54. |
How do you calculate the rate of excretion by kidneys? |
| A. | Rate of filtration – the rate of secretion – Rate of absorption |
| B. | Rate of filtration + rate of secretion – Rate of absorption |
| C. | Rate of filtration + rate of secretion + Rate of absorption |
| D. | Rate of filtration – the rate of secretion + Rate of absorption |
| Answer» B. Rate of filtration + rate of secretion – Rate of absorption | |
| 55. |
What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug? |
| A. | 3ml/sec |
| B. | 0.3ml/sec |
| C. | 1ml/sec |
| D. | 1.3ml/sec |
| Answer» D. 1.3ml/sec | |
| 56. |
Which one of the following is the principal organ for drug excretion? |
| A. | Lungs |
| B. | Liver |
| C. | Kidneys |
| D. | Sweat glands |
| Answer» C. Kidneys | |
| 57. |
Compounds excreted in bile is classified into 3 categories. Which one of the following does not come under the categories? |
| A. | Drugs with bile/plasma concentration ratio approximately 1 |
| B. | Drugs with bile/plasma concentration ratio between 10-1000 |
| C. | Drugs with bile/plasma concentration ratio of less than 1 |
| D. | Drugs with bile/plasma concentration ratio above 1000 |
| Answer» D. Drugs with bile/plasma concentration ratio above 1000 | |
| 58. |
What is the molecular weight cut off for biliary excretion? |
| A. | Less than 300 Dalton |
| B. | More than 300 Dalton |
| C. | Less than 200 Dalton |
| D. | More than 200 Dalton |
| Answer» B. More than 300 Dalton | |
| 59. |
What is the equation for biliary clearance? |
| A. | No such equation is there |
| B. | Biliary excretion rate/ plasma drug concentration |
| C. | Plasma drug concentration / biliary excretion rate |
| D. | Plasma drug concentration / Bile flow * biliary drug concentration |
| Answer» B. Biliary excretion rate/ plasma drug concentration | |
| 60. |
For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance? |
| A. | 1.50 ml/mm |
| B. | 1.75 ml/mm |
| C. | 2.75 ml/mm |
| D. | 3 ml/mm |
| Answer» B. 1.75 ml/mm | |
| 61. |
Which compounds are excreted through the lungs? |
| A. | Lipophilic |
| B. | Gaseous |
| C. | Liquid and hydrophilic |
| D. | Solid less than 100 Dalton |
| Answer» B. Gaseous | |
| 62. |
What is the pH of the milk secreted by human mothers? |
| A. | 6.4-7.6 |
| B. | 5.4-6.6 |
| C. | 7-8 |
| D. | 6-7 |
| Answer» A. 6.4-7.6 | |
| 63. |
What is the mechanism of drug excretion for skin excretion? |
| A. | Active secretion |
| B. | Glomerular secretion |
| C. | Passive diffusion |
| D. | Passive reabsorption |
| Answer» C. Passive diffusion | |
| 64. |
What is the mechanism of drug excretion for biliary excretion? |
| A. | Active secretion |
| B. | Glomerular secretion |
| C. | Passive diffusion |
| D. | Passive reabsorption |
| Answer» A. Active secretion | |
| 65. |
Which of the following is not a factor influencing pulmonary excretion? |
| A. | Pulmonary blood flow |
| B. | The solubility of volatile substance |
| C. | Rate of respiration |
| D. | Heart rate |
| Answer» D. Heart rate | |
| 66. |
How is renal clearance expressed mathematically? |
| A. | Rate of urinary excretion/plasma drug concentration |
| B. | Plasma drug concentration/rate of urinary excretion |
| C. | 1/ Plasma drug concentration |
| D. | 1/rate of urinary excretion |
| Answer» A. Rate of urinary excretion/plasma drug concentration | |
| 67. |
What is the driving force for glomerular filtration? |
| A. | Concentration gradient |
| B. | Hydrostatic pressure of plasma |
| C. | High amount of aqueous pores |
| D. | Hydrostatic pressure of blood flow |
| Answer» D. Hydrostatic pressure of blood flow | |
| 68. |
Which of the following compounds are used as agents to determine Glomerular Filtration Rate? |
| A. | Calcium ion |
| B. | Albumin |
| C. | Creatinine |
| D. | Calcium carbonate |
| Answer» C. Creatinine | |
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