McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) .
Chapters
| 51. |
How pH alteration of the drug microenvironment is done? |
| A. | Altering the pH while the administration |
| B. | In situ salt formation |
| C. | Altering the pH of the tissue |
| D. | Formulating the drug in such a way that it gets activated only when it reaches the tissue pH |
| Answer» B. In situ salt formation | |
| 52. |
Which one of the following is used for selective adsorption on insoluble carriers of the drugs? |
| A. | Freeze drying |
| B. | Organic solvent |
| C. | Inorganic clays like bentonite |
| D. | Creating metastable polymorphs |
| Answer» C. Inorganic clays like bentonite | |
| 53. |
Which of the following is used in solvent deposition method of enhancing bioavailability? |
| A. | Freeze drying |
| B. | Organic solvent |
| C. | Inorganic clays like bentonite |
| D. | Creating metastable polymorphs |
| Answer» B. Organic solvent | |
| 54. |
Which of the following is used in solid solutions method of enhancing bioavailability? |
| A. | Highly water-soluble compound |
| B. | Organic solvent |
| C. | Inorganic clays like bentonite |
| D. | Creating metastable polymorphs |
| Answer» A. Highly water-soluble compound | |
| 55. |
Which of the following is used in molecular encapsulation of drugs for enhancing bioavailability? |
| A. | Highly water-soluble compound |
| B. | Cyclodextrin |
| C. | Inorganic clays like bentonite |
| D. | Creating metastable polymorphs |
| Answer» B. Cyclodextrin | |
| 56. |
What is bioequivalence? |
| A. | Comparison between 3-year-old drugs to the same new drug |
| B. | Comparison between a drugs to another drug |
| C. | Comparison between a drug’s specific characteristics to a defined set of standards |
| D. | Comparison between two or 3 characteristics of a drug to the same characteristics of a different drug |
| Answer» C. Comparison between a drug’s specific characteristics to a defined set of standards | |
| 57. |
What is the chemical equivalence? |
| A. | Two or more drug products contain the same labeled chemical substance in the same amount |
| B. | Two or more drug products contain the same labeled chemical substance in different quantity |
| C. | Two or more drug products contain different labeled chemical substance giving the same therapeutic effect |
| D. | Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect |
| Answer» A. Two or more drug products contain the same labeled chemical substance in the same amount | |
| 58. |
What is pharmaceutic equivalence? |
| A. | Two or more drug products contain the same labeled chemical substance in the same amount |
| B. | Two or more drug products are identical in quality, purity, uniformity, disintegration, dissolution |
| C. | Two or more drug products contain different labeled chemical substance giving the same therapeutic effect |
| D. | Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect |
| Answer» B. Two or more drug products are identical in quality, purity, uniformity, disintegration, dissolution | |
| 59. |
What is bioequivalence? |
| A. | Drug substance reaches the systemic circulation at the same rate in two or more identical dosage |
| B. | Two or more drug products contain the same labeled chemical substance in different quantity |
| C. | Two or more drug products contain different labeled chemical substance giving the same therapeutic effect |
| D. | Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect |
| Answer» A. Drug substance reaches the systemic circulation at the same rate in two or more identical dosage | |
| 60. |
What is therapeutic equivalence? |
| A. | Two or more drug products contain the same labeled chemical substance in the same amount |
| B. | Two or more drug products contain the same labeled chemical substance in different quantity |
| C. | Two or more drug products contain the same labeled chemical substance giving the same therapeutic effect |
| D. | Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect |
| Answer» C. Two or more drug products contain the same labeled chemical substance giving the same therapeutic effect | |
| 61. |
On which individuals study of newly invented medicines are not done? |
| A. | Pregnant and elderly |
| B. | Fasting person |
| C. | Healthy person |
| D. | Adult male |
| Answer» A. Pregnant and elderly | |
| 62. |
What should be the disadvantage of cross over study on volunteers? |
| A. | Minimize the intersubject variability in plasma drug levels |
| B. | Minimize the carry-over effect |
| C. | Minimizes variations due to time effect |
| D. | Takes a lot of time to get the result of the study |
| Answer» D. Takes a lot of time to get the result of the study | |
| 63. |
Two or more drugs contain the same therapeutically active ingredient which elicits same pharmacological effects and can control the disease to the same extent are known to be pharmaceutic equivalent. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» B. False | |
| 64. |
If the bioavailability of test formulation is 80-120% of the reference standard, it is considered to be bioequivalent. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» A. True | |
| 65. |
Bioequivalence is a relative term which denotes that the drug substance reaches the systemic circulation at the same relative rate or time. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» B. False | |
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