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Chapter:

110+ Pharmacokinetics Solved MCQs

in Biopharmaceutics and Pharmacokinetics

These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) .

Chapters

Chapter: Pharmacokinetics
101.

How much time does an intravenously administered drug take to complete a complete circulation?

A. 5-8 min
B. 7-10 min
C. 1-3 min
D. 1 min
Answer» C. 1-3 min
102.

In the equation log C = log Co – KEt/2.303, what does Co stand for _______

A. Plasma drug concentration after 60 min of i.v. injection
B. Plasma drug concentration after 15 min of i.v. injection
C. Plasma drug concentration after 30 min of i.v. injection
D. Plasma drug concentration immediately after i.v. injection.
Answer» D. Plasma drug concentration immediately after i.v. injection.
103.

What is meant by elimination half-life?

A. Time take for half of the amount of drug to get completely eliminated from only the organs
B. Time take for half of the amount of drug to get completely eliminated from only blood
C. Time take for half of the amount of drug to get completely eliminated from only plasma
D. Time take for half of the amount of drug to get completely eliminated from the body as well as plasma
Answer» D. Time take for half of the amount of drug to get completely eliminated from the body as well as plasma
104.

What is the equation to find out the apparent volume of distribution?

A. Amount of drug in the body/plasma drug concentration
B. Plasma drug concentration/amount of drug in the body
C. 1 / plasma drug concentration
D. 1 / Amount of drug in the body
Answer» A. Amount of drug in the body/plasma drug concentration
105.

The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?

A. 625 mg/ml
B. 625 l
C. 625 ml
D. 0.0016 mg/ml
Answer» C. 625 ml
106.

To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?

A. 1080 ml
B. 1080 g
C. 1080 mg
D. 1g/ml
Answer» C. 1080 mg
107.

What is the equation to find out hepatic clearance?

A. Plasma drug concentration/rate of elimination by the kidney
B. Rate of elimination by kidney/plasma drug concentration
C. 1 / rate of elimination by the kidney
D. 1 / plasma drug concentration
Answer» B. Rate of elimination by kidney/plasma drug concentration
108.

Which organs comprise the central compartment in a two compartment model?

A. Muscles
B. Skin
C. Adipose
D. Liver
Answer» D. Liver
109.

Which organ comprises the peripheral compartment in a two compartment model?

A. Liver
B. Lungs
C. Kidneys
D. Muscles
Answer» D. Muscles
110.

Which of the following is not a category of 2 compartment model?

A. Two compartment model with elimination from the central compartment
B. Two compartment model with elimination from the peripheral compartment
C. Two compartment model with elimination from only plasma and blood
D. Two compartment model with elimination from both the compartments
Answer» D. Two compartment model with elimination from both the compartments

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