McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) , Pharmacy .
Chapters
| 201. |
Andreasen apparatus consists of: |
| A. | balance |
| B. | electrodes |
| C. | hydrometer |
| D. | pipette |
| Answer» C. hydrometer | |
| 202. |
When coulter-counter apparatus is employed for powder analysis, the following criterion is important: |
| A. | dispersion medium should be colored |
| B. | dispersion medium should be conducting |
| C. | suspended particles should be charged |
| D. | suspended particles should be spherical |
| Answer» B. dispersion medium should be conducting | |
| 203. |
In coulter-counter, as the particles travel through the orifice, the event that occurs is: |
| A. | conductance between the electrodes increases |
| B. | electronic scanners produce photographs for volume measurement |
| C. | resistance between the electrodes increases |
| D. | sedimentation increases |
| Answer» C. resistance between the electrodes increases | |
| 204. |
Fisher subsieve sizer is used to determine the surface area of the powder. The surface area is measured based on the change in: |
| A. | light transmission of gas that reaches the detector |
| B. | pressure across the compacted powder |
| C. | thermal conductivity of gas across the powdered pack |
| D. | weight of powder when air is passed through the powdered pack |
| Answer» D. weight of powder when air is passed through the powdered pack | |
| 205. |
High repose angle of the granules indicated: |
| A. | bulk density of the granules |
| B. | porosity of the granules |
| C. | roughness of the granule surface |
| D. | smoothness of the granule surface |
| Answer» C. roughness of the granule surface | |
| 206. |
The true density of talc is 2.7 g/cc, the bulk density (g/cc) of talc will be: |
| A. | equal to 2.7 |
| B. | greater than 2.7 |
| C. | less than 2.7 |
| D. | unrelated |
| Answer» C. less than 2.7 | |
| 207. |
The angle of repose values are utilized to: |
| A. | measure the movement of granules from hopper to the table of tabletting/capsule machine |
| B. | select proper containers for capsules of a given mass of powders |
| C. | study the absorption of drugs |
| D. | understand dissolution of medicament |
| Answer» A. measure the movement of granules from hopper to the table of tabletting/capsule machine | |
| 208. |
The term ‘light’ as applied to pharmaceutical powders means: |
| A. | low bulk density |
| B. | low granule density |
| C. | low true density |
| D. | slightly coloured |
| Answer» B. low granule density | |
| 209. |
The type of particle diameter that is obtained by microscope method of evaluation is: |
| A. | projected |
| B. | stokes’ |
| C. | volume |
| D. | volume-surface |
| Answer» A. projected | |
| 210. |
Porosity of a porous powder is defined as: |
| A. | bulk volume/void volume |
| B. | void volume/bulk volume |
| C. | void volume/true volume |
| D. | true volume/bulk volume |
| Answer» B. void volume/bulk volume | |
| 211. |
Which equation is used to convert number distribution to weight distribution |
| A. | Noyes whitney equation |
| B. | Hatch Choate equation |
| C. | Henderson Hasselbalch equation |
| D. | Higuchi equation |
| Answer» B. Hatch Choate equation | |
| 212. |
Coulter counter is used to determine |
| A. | Particle volume |
| B. | Particle Number |
| C. | Particle interaction |
| D. | Viscosity |
| Answer» A. Particle volume | |
| 213. |
The ratio of void volume to bulk volume is known as |
| A. | Bulk density |
| B. | Tapped density |
| C. | Porosity |
| D. | Granule volume |
| Answer» A. Bulk density | |
| 214. |
If Carr's compressibility index value is in between 26 to 31, then flow will be |
| A. | Poor |
| B. | Excellent |
| C. | Passable |
| D. | Very, very poor |
| Answer» A. Poor | |
| 215. |
Hausner Ratio is |
| A. | Tapped density / Bulk density |
| B. | Bulk density / Tapped density |
| C. | bulk volume / void volume |
| D. | void volume / bulk volume |
| Answer» A. Tapped density / Bulk density | |
| 216. |
The powder having low bulk density or large bulk volume is known as |
| A. | Light powder |
| B. | Heavy powder |
| C. | Bulk powder |
| D. | Granular powder |
| Answer» A. Light powder | |
| 217. |
The term Micromeritics was given by |
| A. | J.M. Dalla Valle |
| B. | James Kelvin |
| C. | William Procter |
| D. | Mahadeva Lai Schroff |
| Answer» A. J.M. Dalla Valle | |
| 218. |
Andreasen pipette is widely used method to determine particle size distribution by |
| A. | Microscopy method |
| B. | sedimentation method |
| C. | Sieving method |
| D. | All of the above |
| Answer» B. sedimentation method | |
| 219. |
Porosity is expressed in |
| A. | Percentage |
| B. | Millimeter |
| C. | Gram/Millimeter |
| D. | Newton |
| Answer» A. Percentage | |
| 220. |
Helium Pycnometer is used to determine |
| A. | Size |
| B. | True density |
| C. | Sedimentation rate |
| D. | Surface area |
| Answer» B. True density | |
| 221. |
The porosity of powder is equal to |
| A. | Ratio of void volume to bulk volume. |
| B. | Sum of void volume to bulk volume |
| C. | Product of void volume to bulk volume |
| D. | Void volume only |
| Answer» A. Ratio of void volume to bulk volume. | |
| 222. |
The distance between two tangents on opposite sides of the particle parallel to some fixed direction. |
| A. | Feret's diameter |
| B. | Martin diameter |
| C. | Projected diameter |
| D. | Stoke's diameter |
| Answer» A. Feret's diameter | |
| 223. |
Andreason apparatus consist of |
| A. | Reference electrode |
| B. | Pipette |
| C. | Glass electrode |
| D. | Hydrogen electrode |
| Answer» B. Pipette | |
| 224. |
The physical, chemical, and pharmacologic properties of a drug are directly affected by…… |
| A. | Size |
| B. | Surface area |
| C. | Both of the above |
| D. | None of the above |
| Answer» C. Both of the above | |
| 225. |
............is the science and technology of small particles. |
| A. | Micromeritics |
| B. | Microscopy |
| C. | Rheology |
| D. | None of the above |
| Answer» A. Micromeritics | |
| 226. |
The unit of particle size used is in………… |
| A. | Kilometer (km) |
| B. | Centimeter (Cm) |
| C. | Millimeter (mm) |
| D. | Micrometer (µm) |
| Answer» D. Micrometer (µm) | |
| 227. |
1 micrometer (µm) is equal to |
| A. | 10-5 m |
| B. | 10-6 m |
| C. | 10-7 m |
| D. | 10-8 m |
| Answer» B. 10-6 m | |
| 228. |
Particle size with diameter of 0.5-1.0 Micrometers (µm) is useful for…….. |
| A. | Emulsions |
| B. | Suspensions |
| C. | Both of the above |
| D. | None of the above |
| Answer» C. Both of the above | |
| 229. |
The size of a sphere is freely stated in terms of its............. |
| A. | Area |
| B. | Diameter |
| C. | Radius |
| D. | Volume |
| Answer» B. Diameter | |
| 230. |
…...is the diameter of a sphere having, the same observed area as the particle when viewed normal to its most stable plane. |
| A. | The surface diameter (ds) |
| B. | The projected diameter (dp) |
| C. | The volume diameter (dv) |
| D. | The Stokes diameter (dst) |
| Answer» B. The projected diameter (dp) | |
| 231. |
.... is the number of particles per unit weight. |
| A. | Particle volume |
| B. | Particle number |
| C. | Particle mean |
| D. | Particle weight |
| Answer» B. Particle number | |
| 232. |
…....technique is utilized for estimation of surface diameter ds. |
| A. | Air permeability |
| B. | Vacuum |
| C. | Filtration |
| D. | Weighing |
| Answer» A. Air permeability | |
| 233. |
The ratio of the void volume to the bulk volume of the packing is called as the.................... |
| A. | Tap density |
| B. | Bulk density |
| C. | Followability |
| D. | Porosity |
| Answer» D. Porosity | |
| 234. |
In the photochemical degradation of multisulpha preparation, the order that the reaction follows is: |
| A. | first |
| B. | pseudo first |
| C. | second |
| D. | zero |
| Answer» D. zero | |
| 235. |
The integral rate equation for a reaction (in common notation) is written as log C = log Co - (kt/2.303). When a graph is drawn log c vs. t, the slope will be: |
| A. | negative |
| B. | one |
| C. | Positive |
| D. | Zero |
| Answer» A. negative | |
| 236. |
The integral equation (in common notation) k = x/at (a - x) is concerned with the order: |
| A. | first |
| B. | pseudo first |
| C. | second |
| D. | zero |
| Answer» C. second | |
| 237. |
When a series of steps are involved in a reaction, the ‘overall rate’ of a reaction depends upon the rate(s) of: |
| A. | all steps |
| B. | all steps which follow the slowest step |
| C. | all steps which precede the slowest step |
| D. | the slowest step |
| Answer» C. all steps which precede the slowest step | |
| 238. |
The solid state decomposition of aspirin in presence of moisture follows the order: |
| A. | first |
| B. | pseudofirst |
| C. | second |
| D. | zero |
| Answer» D. zero | |
| 239. |
The reaction rate constant (k) is 2.0 x 10-3 min.-1 for aspirin hydrolysis in 0.1 N hydrochloric acid at 1mg/ml concentration. Under same conditions, if the product contains aspirin 4 mg/ml of the initial concentration, the k value in minutes-1 will be: |
| A. | 0.5 x l0-3 |
| B. | 2.0 x 10-3 |
| C. | 4.0 x 10-3 |
| D. | 8.0 x 10-3 |
| Answer» B. 2.0 x 10-3 | |
| 240. |
A second order reaction follows pseudo-first order reaction, when the concentrations of: |
| A. | two reactants are high |
| B. | two reactants are low |
| C. | one reactant is far higher than the other reactant. |
| D. | two reactants are equal |
| Answer» C. one reactant is far higher than the other reactant. | |
| 241. |
In the study of the rate of a reaction, 100 ml of 0.1 N hydrochloric acid is added to 10 ml methyl acetate for the reaction to occur. The reason for making such a proportion is to make: |
| A. | analysis of degradation is easy |
| B. | reaction to follow first order |
| C. | reaction to proceed slowly |
| D. | reaction to undergo a pseudo first order |
| Answer» D. reaction to undergo a pseudo first order | |
| 242. |
The conversion of trans-stilbene to cis-stilbene follows the molecularity: |
| A. | bimolecular |
| B. | termolecular |
| C. | unimolecular |
| D. | zeromolccular |
| Answer» C. unimolecular | |
| 243. |
In the hydrolysis of sucrose in hydrochloric acid solution, the change in the optical rotation follows the order: |
| A. | pseudofirst |
| B. | pseudo zero |
| C. | second |
| D. | zero |
| Answer» A. pseudofirst | |
| 244. |
In the degradation studies of aspirin suspension, the orders observed initially and at the end, respectively, are: - |
| A. | first, second |
| B. | first, zero |
| C. | second, first |
| D. | zero, first |
| Answer» D. zero, first | |
| 245. |
A prescription of liquid aspirin preparation contained 6.5 g/100 ml. The solubility of aspirin at 25°C is 0.33 g/100 ml. The order of reaction in the kinetic study is: |
| A. | apparent first |
| B. | apparent zero |
| C. | first |
| D. | second |
| Answer» B. apparent zero | |
| 246. |
The time required for the complete degradation of a drug in solution is a finite value. The order of that reaction is: |
| A. | first |
| B. | pseudo first |
| C. | second |
| D. | zero |
| Answer» D. zero | |
| 247. |
Normally, ethyl acetate undergoes hydrolysis in presence of H+ and (OH)-ions. The order of the reaction observed in the acidic and alkaline solutions, respectively, are: |
| A. | first and second |
| B. | pseudo first and second |
| C. | second and first |
| D. | second and pseudo first |
| Answer» B. pseudo first and second | |
| 248. |
In reactions that follow first order kinetics, half life is expressed by equation: |
| A. | 0.693/k1 |
| B. | 0.301/k1 |
| C. | 0.105/k1 |
| D. | k1/0.693 |
| Answer» A. 0.693/k1 | |
| 249. |
The units for the specific rate constant for a second order reaction are: |
| A. | liter/moles.sec |
| B. | liter.sec/moles |
| C. | moles/liter.sec |
| D. | moles.sec/liter |
| Answer» A. liter/moles.sec | |
| 250. |
The half life of a first order reaction is 4 years. What is its shelf life (in years)? |
| A. | 0.02 |
| B. | 0.03 |
| C. | 0.17 |
| D. | 0.61 |
| Answer» D. 0.61 | |
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