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300+ Physical Pharmaceutics 2 Solved MCQs

These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) , Pharmacy .

Chapters

Chapter: Rheology
101.

In psedoplastic flow as shear stress increases, shear rate...............

A. Increases
B. Increases but linear
C. Increases but not linear
D. Decreases
Answer» C. Increases but not linear
102.

Dilatant materials are frequently called as...............

A. strain-thinning systems
B. shear-thickening systems
C. shear-thinning systems
D. strain-thinning systems
Answer» B. shear-thickening systems
103.

The Rheogram of thixotropic material determined by...................

A. Duration through which sample is exposed to any one shear rate.
B. Rate at which shear increased or decreased.
C. Both of the above
D. None of the above
Answer» C. Both of the above
104.

....... is the isothermal and moderately slow recovery on standing of material of which stability lost owing to shearing.

A. Thermochemistry
B. Viscosity
C. Entiotropy
D. Thixotropy
Answer» D. Thixotropy
105.

......is the alteration in the shape and the size of a body owing to applied external forces and internal forces.

A. Deformation
B. Formation
C. Conjugation
D. None of the above
Answer» A. Deformation
Chapter: Deformation of Solid
106.

A wetting agent is included in the formulation of a suspension, particularly when the suspended particles:

A. are hydrophobic
B. are more denser than the vehicle
C. are water soluble
D. have lesser interfacial tension
Answer» A. are hydrophobic
107.

For a flocculated suspension, one of the following criterion is satisfied or established

A. High inter-particle repulsions
B. strong inter-particle attractions
C. weak inter-particle attractions
D. weak inter-particle repulsions
Answer» C. weak inter-particle attractions
108.

In stokes’ relationship, a parameter that greatly changes the velocity of settling is:

A. density of the liquid
B. density of particle
C. radius of the particle
D. viscosity of the medium
Answer» C. radius of the particle
109.

The protamine-zinc insulin suspension is prepared by a method viz.,:

A. altered pH precipitation
B. dispersion method
C. double decomposition
D. organic solvent precipitation
Answer» A. altered pH precipitation
110.

Methyl cellulose is a polymer, which is of a type:

A. anionic
B. amphilytic
C. cationic
D. non-ionic
Answer» D. non-ionic
111.

For a flocculated suspension the degree of flocculation is observed to be one. The sedimentation volume is also 1 (one). These values, respectively, indicate the limits:

A. lower and lower
B. lower and upper
C. upper and lower
D. upper and upper
Answer» B. lower and upper
112.

For an ideal suspension, the sedimentation volume should be:

A. equal to one
B. less than one
C. more than one
D. zero
Answer» A. equal to one
113.

In case of suspensions, all statements below are true EXCEPT that:

A. it contains a suspending agent
B. it does not include a preservative
C. it is an injectable preparation
D. it is an oral preparation
Answer» B. it does not include a preservative
114.

In practice, an acceptable suspension should have particles:

A. of nearly 0.1 micrometer
B. which can be readily re-dispersible after they settle
C. which should form a cake after settling
D. should not settle
Answer» B. which can be readily re-dispersible after they settle
115.

For oral administration of a suspension to a patient, which one of the factors is the most important?

A. acceptable color and odour
B. polyumorphism
C. specific surface area
D. viscosity
Answer» A. acceptable color and odour
116.

Which one of the following properties is applicable to suspensions?

A. Brownian movement
B. laminar flow
C. rapid rate of sedimentation
D. strokes’ law
Answer» C. rapid rate of sedimentation
117.

Suspended particles become flocculated in a suspension, because:

A. attractive forces between particles are appreciable
B. particles are packed closely
C. repulsive forces between particles are appreciable
D. vehicle rejects the particles
Answer» A. attractive forces between particles are appreciable
118.

Structured vehicle is included in the formulation of a suspension, in order to:

A. decrease the interfacial tension
B. prevent the caking of the sediment
C. prevent the sedimentation of particles
D. reduce the size by chemical me
Answer» A. decrease the interfacial tension
119.

In the preparation of a structured vehicle, which one of the following substances is used?

A. bismuth subnitrate
B. ethyl alcohol
C. glycerin
D. methyl cellulose
Answer» D. methyl cellulose
120.

Which type of colloidal material is used commonly in the preparation of a structured vehicle?

A. association
B. hydrophilic
C. hydrophobic
D. inorganic
Answer» B. hydrophilic
121.

When charcoal powder is dusted on the surface of water, the contact angle (in degrees) that the charcoal exhibits is:

A. zero
B. one
C. 90
D. 180
Answer» D. 180
122.

A maximum sedimentation volume will be obtained when zeta potential is:

A. negative
B. neutral
C. positive
D. zero
Answer» D. zero
123.

A substance is dissolved in water. The suspension has exhibited a negative apparent zeta potential. Identify the related substance.

A. aluminum chloride
B. bismuth subnitrate
C. gelatin
D. sulfaguanidine
Answer» D. sulfaguanidine
124.

Calcium hydrogen phosphate is dissolved in water. The apparent zeta potential initially is:

A. negative
B. neutral
C. positive
D. zero
Answer» A. negative
125.

Which one of these preparations is NOT qualified as a suspension.

A. barium meal for radiodiagnostic use
B. calamine lotion for antiseptic use
C. procaine penicillin G for intramuscular injection
D. vitamin B complex tonic as nutritional supplement
Answer» D. vitamin B complex tonic as nutritional supplement
126.

The ratio of the ultimate volume of sediment to the actual volume of sediment before settling is called

A. Sedimentation volume
B. Degree of flocculation
C. Emulsification volume
D. phase volume ratio
Answer» A. Sedimentation volume
127.

The ratio of the sedimentation volume in case of flocculated suspension to the sedimentation volume in case of deflocculated suspension is called

A. Sedimentation volume
B. Degree of flocculation
C. Emulsification volume
D. phase volume ratio
Answer» B. Degree of flocculation
128.

The size of dispersed particles in coarse dispersion ranges from

A. 1 µm to 100 µm.
B. 1 nm to l00nm
C. 1mm to 100cm
D. Less than 1 µm
Answer» A. 1 µm to 100 µm.
129.

Which of the following are the desired features of good suspension:

A. The particles which settle down should not deposit at the bottom as hard cake. They must be easily re-suspended by moderate shaking.
B. It should be free from grittiness.
C. It should be stable in case of physical, chemical and microbial attack.
D. All of the above
Answer» D. All of the above
130.

In flocculated suspension, the rate of sedimentation is

A. Low
B. More
C. Zero
D. 50%
Answer» B. More
131.

If zeta potential of a suspension is high, then the system will be considered as

A. Deflocculation
B. Flocculation
C. Emulsion
D. Sedimentation
Answer» A. Deflocculation
132.

Which of the following is/are the properties of flocculated suspension?

A. Rate of sedimentation is high
B. On shaking sediment can be easily redispersed
C. It does not form hard cake
D. All of the above
Answer» D. All of the above
133.

The value of sedimentation volume (F) gives a knowledge about the____________of the suspension

A. physical stability
B. Incompatibility
C. Solubility
D. All of the above
Answer» A. physical stability
134.

Suspension is example of

A. Biphasic liquid dosage form
B. Solid dosage form
C. Semi-solid dosage form
D. All of the above
Answer» A. Biphasic liquid dosage form
135.

Acetates and Citrates are

A. Buffering agent
B. Colouring agents
C. Thickening agent
D. Flocculating agents
Answer» A. Buffering agent
Chapter: Coarse Dispersion- Emulsion
136.

In an emulsion, the velocity of sedimentation is found to be negative. It means that the creaming is:

A. absent
B. in both the directions
C. in downward direction
D. in upward direction
Answer» D. in upward direction
137.

The density of the dispersed phase is more than that of the dispersion medium. According to the Stokes' equation, the creaming is:

A. at the center of the emulsion
B. in both the directions
C. in downward direction
D. in upward direction
Answer» C. in downward direction
138.

When oil and water are triturated together, the interfacial free energy was observed to be increased. What does it indicate?:

A. decrease in the interfacial tension
B. decrease in the stability
C. increase in stability
D. stable film formation
Answer» B. decrease in the stability
139.

For a stable emulsion, the phase volume ratio is generally about:

A. 26/74
B. 52/48
C. 74/26
D. 74/100
Answer» B. 52/48
140.

The HLB range of an emulsifier employed in the preparation of water-in-oil emulsion is:

A. 3 to 6
B. 7 to 12
C. 13 to 15
D. more than 15
Answer» A. 3 to 6
141.

In case of emulsions, the viscosity immediately after preparation and during storage, respectively, will be:

A. higher and will gradually decrease
B. higher and gradually increase
C. lower and gradually decrease
D. lower and gradually increase
Answer» C. lower and gradually decrease
142.

The distribution of globules is not uniform in an emulsion. This stage is termed as:

A. breaking
B. caking
C. coalescence
D. creaming
Answer» D. creaming
143.

An o/w microemulsion is prepared using a hydrophilic surfactant. The appearance of the microemulsion is:

A. intense white
B. milky white
C. translucent
D. tr
Answer» A. intense white
144.

Emulsions are defined as thermodynamically unstable systems. The events that follow sequentially towards instability are:

A. coalescence, breaking, creaming and flocculation
B. coalescence, flocculation, creaming and breaking
C. flocculation, creaming, breaking and coalescence
D. flocculation, creaming, coalescence and breaking
Answer» D. flocculation, creaming, coalescence and breaking
145.

In the stability of emulsion, which instability step is prevented by emulsifiers?:

A. breaking
B. coalescence
C. creaming
D. flocculation
Answer» B. coalescence
146.

An ‘emulsion within emulsion’ is designated as:

A. o/w/w
B. w/o/o
C. w/o/o/w
D. w/o/w
Answer» D. w/o/w
147.

The main function of an emulsifier in the preparation of an emulsion is to:

A. develop a condensed membrane layer film
B. increase the repulsions between globules coming together
C. increase the surface free energy
D. reduce the interfacial tension
Answer» A. develop a condensed membrane layer film
148.

An emulsifier can be regarded as superior, if its mechanism of action is based on the principle of:

A. developing solid adsorption film
B. forming monomolecular adsorption film
C. generating multimolecular adsorption film
D. increasing interfacial energy
Answer» B. forming monomolecular adsorption film
149.

An emulsifier is considered to be ideal, if it is soluble in:

A. aqueous, oil and gas phases
B. aqueous phase only
C. both aqueous and oil phase
D. oil phase only
Answer» C. both aqueous and oil phase
150.

On commercial scale, emulsions are prepared by::

A. centrifugation
B. dialysis
C. freezing
D. homogenization
Answer» D. homogenization

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