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300+ Physical Pharmaceutics 2 Solved MCQs

These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: Bachelor of Pharmacy (B. Pharma) , Pharmacy .

Chapters

Chapter: Coarse Dispersion- Emulsion
151.

Microemulsion is NOT considered to be a true emulsion, because:

A. appearance is transparent
B. emulsifier is not used
C. immiscible phase is absent
D. internal phase is not spherical
Answer» C. immiscible phase is absent
152.

A variety of factors would influence the rate of creaming in an emulsion. The factor open to formulation pharmacist is to regulate:

A. density of dispersion medium
B. density of dispersed phase
C. globule size
D. volume of dispersion medium
Answer» C. globule size
153.

Normally preservatives are added to an emulsion. One of the following statements is true.

A. amount of the preservative added is below minimum inhibitory concentration
B. emulsifier should enhance the preservative action
C. preservatives remain in the aqueous phase
D. preservatives stay in the oil phase
Answer» C. preservatives remain in the aqueous phase
154.

For the formulation of w/o emulsion, the coalescence rate of:

A. w/o has no relationship to the type of emulsion formed
B. o/w is equal to w/o coalescence rate
C. o/w is greater than w/o coalescence rate
D. w/o is greater than the o/w coalescence rate
Answer» C. o/w is greater than w/o coalescence rate
155.

Auxiliary emulsifying agents are used to stabilize the emulsion. They act on the principle:

A. adjusting the HLB value
B. strengthening the nonpolar tails of the emulsifier ^
C. strengthening the polar heads of the emulsifier
D. thickening the continuous phase
Answer» D. thickening the continuous phase
156.

Emulsion have a ......... shelf life

A. short
B. no
C. large
D. none of the above
Answer» A. short
157.

Creaming is a.......... process

A. reversible
B. irreversible
C. A & B
D. difficult to predict
Answer» A. reversible
158.

O/W emulsions normally cream .........

A. up first & down then
B. upward
C. downward
D. none of the above
Answer» B. upward
159.

Microemulsions contain globules of the size about .........

A. 10 micro meter
B. 1 micro meter
C. 0.1 micrometer
D. 0.01 micrometer
Answer» D. 0.01 micrometer
160.

Downward creaming means ........ rate of sedimentation

A. negative
B. positive
C. same
D. no change
Answer» A. negative
161.

A mixture of span 20 and tween 20 forms....... type of emulsion

A. W/O
B. O/W
C. Milky
D. Hard
Answer» A. W/O
162.

Density of oily phase increased by addition of .......

A. Butter
B. Coconut oil
C. water
D. brominated oils
Answer» C. water
163.

Near CMC, micelles of the surfactant molecules assume the shape of

A. spherical
B. layered
C. rod shaped
D. cylindrical
Answer» A. spherical
164.

Which one of the following emulsifier is used to stabilise the emulsion of W/O type

A. SLS
B. Span 20
C. Tween 20
D. Tragacanth
Answer» B. Span 20
165.

Creaming in emulsion can be controlled by regulating

A. density of dispersed phase
B. density of dispersion medium
C. globule size
D. volume of dispersion medium
Answer» C. globule size
166.

An emulsifier is considered to be ideal, if it is soluble in

A. Aqueous phase
B. oily phase
C. A & B
D. none of the above
Answer» C. A & B
167.

In the stability of emulsion, which important instability step should be prevented?

A. Breaking
B. Coalescence
C. Flocculation
D. Creaming
Answer» B. Coalescence
168.

Emulsions made with tweens are

A. W/O
B. O/W
C. Clear
D. Unstable
Answer» B. O/W
169.

The HLB system is used classify

A. Flavours
B. Colours
C. Surfactants
D. Perfumes
Answer» C. Surfactants
170.

Emulsion containing more than two phases are called as

A. Mixed emulsion
B. Multiple emulsion
C. Complex emulsion
D. none of the above
Answer» B. Multiple emulsion
171.

Emulsion is

A. stable preparation
B. thermodynamically unstable preparation
C. biphasic system
D. B & C
Answer» D. B & C
172.

Which of the following is/ are the theories of emulsification?

A. Monomolecular adsorption theory
B. Multimolecular adsorption theory
C. Solid Particle Adsorption theory
D. All of the above
Answer» D. All of the above
173.

Which of the following is not the cause of Instability in emulsion

A. Upward Creaming
B. Phase inversion
C. Downward creaming
D. Mottling
Answer» D. Mottling
174.

Which of the following is a reversible phenomenon

A. Creaming
B. Coalescence
C. Breaking
D. All of the above
Answer» A. Creaming
175.

The phase inversion occur due to

A. changes in type of emulsifying agent
B. change in phase volume ratio.
C. Both a and b
D. None of the above
Answer» C. Both a and b
176.

Which of the following is used as antioxidants for emulsified systems

A. Dodecyl gallate,
B. Butylated hydroxyanisole (BHT),
C. Butylated hydroxytoluene (BHT)
D. All of the above
Answer» D. All of the above
177.

Which of the following is identification test for emulsion

A. Dilution test
B. Cobalt Chloride Test
C. Conductivity Test
D. All of the above
Answer» D. All of the above
178.

When an emulsion is exposed to ultra-violet radiations. If the continuous fluorescence is observed under microscope, then it is_____________ type emulsion.

A. w/o
B. o/w
C. microemulsion
D. Nano emulsion
Answer» A. w/o
179.

Dry Gum Method is also known as

A. Continental method.
B. English method
C. Bottle method
D. Forbe's method
Answer» A. Continental method.
180.

In Dry gum method, 4:2:1 consist of

A. 4 parts oil, 2 parts water, and 1 part emulsifier
B. 4 parts water, 2 parts oil, and 1 part emulsifier
C. 4 parts emulsifier, 2 parts water, and 1 part emulsifier
D. 4 parts oil, 2 parts emulsifier and 1 part water
Answer» A. 4 parts oil, 2 parts water, and 1 part emulsifier
181.

The rheological property of emulsion can be controlled by

A. nature and concentration of emulsifying system
B. particle size of dispersed phase
C. viscosity of continuous phase
D. All of the above
Answer» D. All of the above
182.

The suspensions having particle size................... are categorized as coarse suspension.

A. Greater than ~1 mm
B. Greater than-10 mm
C. Both of the above
D. None of the above
Answer» A. Greater than ~1 mm
183.

............ exists when dispersed solid particles in a suspension retain change in relation their adjoining liquid medium.

A. Surface area
B. Surface potential
C. Surface volume
D. None of the above
Answer» B. Surface potential
184.

The equal distribution of all the ions in solution retain by……

A. Electric forces
B. Thermal motion
C. Both of the above
D. None of the above
Answer» C. Both of the above
185.

The flocculated suspension is one in which zeta potential of particle is…… .

A. -05 to +05 mV
B. -10 to+10 mV
C. -20 to+20 mV
D. -30 to+30 mV
Answer» C. -20 to+20 mV
186.

...... determines the movement of charged particles via a liquid under the impact of an applied potential difference.

A. Electrophoresis
B. Electrosmosis
C. Surface charge
D. Static movement
Answer» A. Electrophoresis
187.

..........is produced by forcing a liquid to course through a stationary solid phase.

A. Electrosmosis
B. Electrophoresis
C. The sediment potential
D. The streaming potential
Answer» D. The streaming potential
188.

The flocculated suspensions sediment.............

A. Slowly
B. Quickly
C. More quickly
D. None of the above
Answer» C. More quickly
189.

..........suspension involves individual particle settling.

A. Flocculated
B. Deflocculated
C. Both of the above
D. None of the above
Answer» B. Deflocculated
190.

Structured vehicles are also termed as or..............

A. Thickening
B. Suspending agents
C. Both of the above
D. None of the above
Answer» C. Both of the above
191.

....... is the concentration of globules at the top or bottom of the emulsion.

A. Creaming
B. Cracking
C. Phase inversion
D. State
Answer» A. Creaming
Chapter: Micromeritics
192.

Which of the following properties of a particle significantly affects the physical, chemical and biological properties of the drug?

A. density
B. sedimentation
C. size
D. surface area
Answer» D. surface area
193.

It is difficult to express the size of particles in a meaningful diameter.

A. irregular in shape
B. irregular surface
C. spherical shape
D. uniform in size
Answer» A. irregular in shape
194.

The type of a particle diameter obtained largely depends on:

A. method by which it is determined
B. nature of the powder
C. procedure by which it is calculated
D. way it is defined and described
Answer» A. method by which it is determined
195.

When cumulative percent frequency on a probability scale is plotted against logarithm of the particle size, 50 percent on the probability scale gives the powder particle diameter of:

A. arithmetic mean
B. arithmetic mode
C. geometric mean
D. harmonic mean
Answer» C. geometric mean
196.

Which one of these distributions is more important in the design of dosage forms?

A. Gaussian
B. normal
C. number
D. weight
Answer» D. weight
197.

In the formulation development of emulsions and suspensions, what type of diameter is important?

A. length number
B. projected
C. sieve
D. stokes
Answer» D. stokes
198.

Sieving method is used for size distribution analysis of powder. The disadvantage of this method is:

A. agglomerates can be identified
B. attrition of powder is possible
C. large number of sieves are required
D. tedious and time consuming
Answer» B. attrition of powder is possible
199.

While using sedimentation method for size analysis, addition of a deflocculating agent to a suspension is necessary in order to:

A. accelerate the process of sedimentation
B. make the particles spherical
C. prevent the aggregation
D. satisfy Reynolds number
Answer» C. prevent the aggregation
200.

Stokes’ law cannot be used, if Reynolds number is more than:

A. 0.2
B. 1.8
C. 9.0
D. 18.0
Answer» A. 0.2

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