Chapter: Biotechnology Principles and Processes
501.

Particle bombardment technique is also known as .....

A. Lipofection
B. Electroporation
C. Biolistic
D. Micro injection
Answer» B. Electroporation
502.

Which enzyme is used to break the membrane to relase plant DNA ?

A. Lysozyme
B. Chitinase
C. Cellulose
D. All the above
Answer» A. Lysozyme
503.

Which enzyne is used to break the membrane to relase animal DNA ?

A. Lysozyme
B. chitinase
C. Celluose
D. All the above
Answer» B. chitinase
504.

Which is the first step in the process recombinant DNA technology ?

A. denaturing of DNA
B. Annealing of DNA
C. Isolation of Donor DNA
D. Down streaming
Answer» A. denaturing of DNA
505.

Which primers are used in annealing during amplification of gene ?

A. Reverse primers
B. Forward primers
C. Oligo nucleotide primer
D. Internal primers
Answer» A. Reverse primers
506.

Which of the following is related with genetic engineering ?

A. Breeding
B. somatic hybridization
C. mutation
D. Transgenic
Answer» D. Transgenic
507.

What is C - DNA ?

A. circular DNA
B. Cloned DNA
C. DNA produced from reverse transcription of RNA
D. Cytoplasmic DNA
Answer» C. DNA produced from reverse transcription of RNA
508.

Which of the bollowing statement is incorrect ?

A. cosmid contains gene coding for viral protein
B. cosmid relpicates like plasmids
C. cosmid has antibioticresistant marker gene
D. cos sit has 12 bases helping to join complete genome to make it circular
Answer» A. cosmid contains gene coding for viral protein
509.

The genetic recombinants obtained by in sertion of plasmid into 1 phage genome is called

A. cosmid
B. plasmid
C. phagmid
D. foreign DNA
Answer» A. cosmid
510.

TATAATG sequnce near the RNA start point of phokaryotic promoter is......

A. NICKS
B. DNA marker
C. pallindrome
D. pribnow box
Answer» D. pribnow box
511.

Exonucleases cleaving nucleotides one at a time from the end of polynucleotide chain are.

A. Specific for 5’ end of RNA strand
B. specific for 3’ end of RNA strand
C. specific for both 5’ and 3’ ends of nucleotide strand
D. Non- specific for 5’ and 3’ ends of nucleotide
Answer» B. specific for 3’ end of RNA strand
512.

Genes that are involved in turning on or off the transcription of a set of structural genes are called

A. Polymorphic genes
B. operator gene
C. Rebundant gene
D. Regulatory gene
Answer» C. Rebundant gene
513.

Enzymes used in PCR is ....

A. taq polymerase
B. gyrase
C. transcriptase
D. hexokinase
Answer» C. transcriptase
514.

What are structure labelled A & B respectively

A. EcoRv restriction endonuclease and E coRv ligase
B. EcoRv ligase and EcoRv nuclease and EcoRvmethlase
C. Eco–– Rv restriction endo EcoRv methylase
D. EcoRv Polymerase and EcoRv methylase
Answer» A. EcoRv restriction endonuclease and E coRv ligase
515.

Can you pick up from the figure how bacteria protects its own genone from degradation by restreiction endonuclease ?

A. site specific coupling
B. site specific oxidizing
C. site specific oxidizing
D. site specific methylases
Answer» D. site specific methylases
516.

This is figure of plasmid P BR322 Identiby what represented by A, B, and C

A. A TcR, B ApR and C EcorI
B. A TcR, B EcoRI and C ApR
C. A - EcorI, B ApR and C TcR
D. A ApR, B TcR and C EcoRz
Answer» D. A ApR, B TcR and C EcoRz
517.

These are important set of enzymes used in biotechnology Match them with exact role
P Taq DNa Polymerase (i) cutting single stranded part of DNA
Q S I nuclease (ii) Ligase
R Restriction endo nuclease (iii) Thermostable enzyme
S mole cular glue (iv) cutting pallindromic sequences
(v) union of pallindromic sequences
P Q R S

A. (iii) (iv) (i) (ii)
B. (iii) (v) (iv) (ii)
C. (iv) (i) (v) (ii)
D. (iii) (iv) (i) (ii)
Answer» C. (iv) (i) (v) (ii)
518.

Match the column I and column II
P Radio active andibody (a) substance that can be constructed in the laboratory
Q Artificial gene (b) substance that can be used to identify colonies of geneticully engineered bacteria that makes particular gene product
R Amplification (c) Abnormal enhanced replication of a plasmid many copies of plasmid in each cell
S To produce clones (d) A large population of idential cells
T short gun cloning (e) The use of entire array of genes of an organism in order to obtain particular gene product
P Q R S T

A. b a c d e
B. a c b d e
C. a c d b e
D. b c e d a
Answer» A. b a c d e
519.

For transformation, micro particles coated with DNA are bombarded with gene gun made up of.

A. Platinum or Zinc
B. Silicon or Platinum
C. Gold or tungsten
D. Silver or Platinum
Answer» C. Gold or tungsten
520.

PCR and Restriction fragment lenth Polymorphism are the methods for. (AIPMT-2012)

A. genetic transtormation
B. DNA Sequencing
C. DNA finger printing
D. Study of enzymes
Answer» D. Study of enzymes
521.

The linking of antibiotic resistance gene with the plasmid Vector became possible with

A. DNA ligase
B. Exonuclease
C. Endo nuclease
D. DNA Polymerase
Answer» C. Endo nuclease
522.

Gel electrophoresis is used for--

A. Isolation of DNA molecule
B. Cutting of DNA in to fragments
C. Separation of DNA fragments according to their size
D. Construction of recombinant DNA by joining with cloning Vector
Answer» C. Separation of DNA fragments according to their size
523.

Gentic engineering has been sucessfully used for producing ___ (CBSE-2010)

A. trangenic models for studying new treatments for Certain cardiac diseases.
B. transgenic Cow - Rosie which produces high fat milk for making ghee.
C. animals linke bulies for farm work as they have super power.
D. transgenic mice for testing safety of polio Vaccine before use in humans.
Answer» D. transgenic mice for testing safety of polio Vaccine before use in humans.
524.

Match the following and choose the correct combination from the option given ... (Karnatak PMT-2005)
Column I Column II
(a) Escherichia coli 1 - nif gene
(b) Rhizobium meliloti 2 - digestion of hydrocarbons of crude oil
(c) Bacilius thuringiensis 3 - human insulin production
(d) Pseudomonas putida 4 - Biocontrol of fungal disease
5 - biodegradable insecticide

A. A = 3, B = 1, C = 5, D = 4
B. A = 1, B = 2, C = 3, D = 4,
C. A = 2, B = 1, C = 3, D = 4
D. A = 4, B = 3, C = 1, D = 2
Answer» C. A = 2, B = 1, C = 3, D = 4
525.

Find the incorrrect statement

A. Gene therapy is a genetic engineering technique used to treat disease at molecular level by replacing defective genes with normal genes.
B. Calcitonin is a medically useful recombinant product in the treatment of intetility
C. Bt toxin is a Biodegradable insecticide obtained from bacillis thuringiensis
D. Trichoderma sp. is a biocontrol agent for fungal diseases of plants
Answer» A. Gene therapy is a genetic engineering technique used to treat disease at molecular level by replacing defective genes with normal genes.
526.

Production of a human protein in bacteria genetic engineering is possible because

A. bacterial cell can carry out the RNA splicing reactions
B. the human chromosome can replicate in bacterial cell
C. the mechanism of gene regulation is identical in human and bacteria
D. The genetic code is universal
Answer» C. the mechanism of gene regulation is identical in human and bacteria
527.

The basis of DNA finger printing is

A. The double helix
B. Errors in base sequence
C. Poly morphism in sequence
D. DNA replication
Answer» D. DNA replication
528.

A genetically engineered microorganism used successfully in biomediation of oil spillg is species of (CBSE-2007)

A. Trichoderma
B. Xamthomonas
C. Bacillus
D. Pseudomonas
Answer» C. Bacillus
529.

What is the function of Restriction endonuclease ? (AIPMT -2006)

A. Restricts the synthesis of DNA inside the nucleus
B. Synthesizes DNA
C. Cuts DNA molecule randomly
D. cuts DNA molecule at specific sites
Answer» D. cuts DNA molecule at specific sites
530.

The nuclease enzyme which begins its attack from Free end of a polynucleotide is

A. Exonuclease
B. Kinase
C. Polymerase
D. Endonuclease
Answer» A. Exonuclease
531.

Identify the Plasmid (ET 2004)

A. Alu I
B. Hind III
C. ECORI
D. PBR322
Answer» C. ECORI
532.

Molecular scissors, which cut DNA at specific site (Kerala-2004)

A. ligase
B. cellulase
C. pectinase
D. Polymerase
Answer» E.
533.

In transgenics the experession of transce in the target tissue is known by (CBSE-2004)

A. Enhancer
B. Transgene
C. Promoter
D. Reporter
Answer» A. Enhancer
534.

Variable number of tender repeats (VTNR) in the DNA molecule are highly useful in

A. monoclonal antibody production
B. DNA finger printing
C. Recombinant DNA technology
D. stem cell culture
Answer» B. DNA finger printing
535.

Which one of the following bacteria has found extensive use in genetic engineering work in plants ?

A. Agrobacterium tamefaciens
B. Clostridium septicum
C. Xanthomonas citri
D. Bacilius Coagulens
Answer» A. Agrobacterium tamefaciens
536.

What does Bt stand For the Popular crop Bt Cotton ?

A. Best
B. Best type
C. Biotechnology
D. Bacilius tomentosta
Answer» E.
537.

The total number of nitrogenous bases in human genome is estimated to be about

A. 35 million
B. 3.1 million
C. 3.5 million
D. 3.5 thousand
Answer» D. 3.5 thousand
538.

Name of the drug used in cancer treatment produced by using biotechnology is .....

A. HGH
B. TSH
C. Insulin
D. Interfern
Answer» C. Insulin
539.

Which of the following pair is correctly matched ?

A. - central dogma - codon
B. - Okazaki fragments - splicing
C. RNA Polymerase - RNA Primer
D. Restriction enzymes - genetic engineering
Answer» C. RNA Polymerase - RNA Primer
540.

First Biochemical to be Producod commer cially by microbial cloning and genetic engineering is ___

A. interferom
B. penicillin
C. human insulin
D. Fertility factors
Answer» A. interferom
541.

First hormone prepared by genetic engineering is ....

A. Insulin
B. Oxytocin
C. adrenaline
D. Somatotropin
Answer» A. Insulin
542.

A technology which has found immense use in solving cases of disputed parentage is

A. DNA finger printing
B. Polymerase chain reaction
C. Recombinant DNA technology
D. Monoclonal antibody production
Answer» A. DNA finger printing
543.

Matching sequence of DNA between two evidences, one of the criminal with the suspect is known as

A. DNA finger printing
B. DNA amplification
C. Gene maping
D. DNA resolution
Answer» D. DNA resolution
544.

Agarose extracted From weeds finds use in ______ (A.I.PMT 2011)

A. spectrophoto metry
B. Tissue culture
C. Gel electrophoresis
D. PCR
Answer» B. Tissue culture
545.

Widely used tool in genetic engineering of crop plants is ____ (AIEEE 2004)

A. protoplast fusion
B. Transposon
C. Micro injection
D. Agrobacterium mediation
Answer» B. Transposon
546.

c DNA Probes are copied from messenger RNA molecule with the help of __

A. Restriction enzyme
B. Reverse transcriptase
C. DNA Polymerase
D. Adenosine deaminase
Answer» D. Adenosine deaminase
547.

Which one of the following pair is wrongly matched ?

A. methanogens - Gobargas
B. Yeast - Ethanol
C. Streptomycetes - Antibiotic
D. Coliborms - vinegar
Answer» D. Coliborms - vinegar
548.

The Prerequisites for biotechnological production of antibiotic is

A. to search an antibiotic producing microorganism
B. to isolate the antibiotic gene
C. to join antibiotic gene with E coli plasmid
D. All of the above (MP PMT 2008)
Answer» D. All of the above (MP PMT 2008)
549.

Which one of the following is now being commercially produced by biotechnological Procedures

A. Nicotine
B. Morphine
C. quinine
D. Insulin
Answer» D. Insulin
550.

Which one of the following is a wrong matching of a microbe and its industrial product while the remaining three are correct

A. clostridium butylicum - lactic acid
B. Aspergillis niger cirric acid
C. yeast - statins
D. Acetobacter aceti - acetic acid (CBSE PMT 2011)
Answer» A. clostridium butylicum - lactic acid

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