McqMate
These multiple-choice questions (MCQs) are designed to enhance your knowledge and understanding in the following areas: All India Pre Medical Test (AIPMT) .
Chapters
| 1. |
Name the conjugated protein used as genetic material in living cells |
| A. | Glyco protein |
| B. | Nucleo protein |
| C. | Metallo protein |
| D. | Lip oprotein |
| Answer» B. Nucleo protein | |
| 2. |
Who supported Griffith effect by molecular explanation ? |
| A. | Hershay and chase |
| B. | Watson, crick Ninenberg |
| C. | Avery , Mc Carty and Macleod |
| D. | Griffith and Avery |
| Answer» C. Avery , Mc Carty and Macleod | |
| 3. |
Synthesis of nucleic acids always takes place in |
| A. | 31 - 51 dicectioon |
| B. | 51 - 31 direction |
| C. | Both ways |
| D. | in any direction |
| Answer» B. 51 - 31 direction | |
| 4. |
What is called Griffith effect ? |
| A. | DNA transcription |
| B. | RNA translation |
| C. | Bacterial transformation |
| D. | Bacterial transduction |
| Answer» C. Bacterial transformation | |
| 5. |
Genetic information is carried by the long chain molecules which are made up of |
| A. | Amino acids |
| B. | Nucleotides |
| C. | Chromosomes |
| D. | Enzymes |
| Answer» B. Nucleotides | |
| 6. |
By which bonds the purine & pyrimidine pairs of Complementary Strands of DNA held together? |
| A. | H - bonds |
| B. | O - bonds |
| C. | C - bonds |
| D. | N - bonds |
| Answer» A. H - bonds | |
| 7. |
State the nature of the 2 Strands of DNA duplex. |
| A. | identical & Complementary |
| B. | Anti parallel & complementary |
| C. | Disimilar & non - complementary |
| D. | Anti parallel & Non - complementary |
| Answer» B. Anti parallel & complementary | |
| 8. |
The code AUG stands for |
| A. | Glycine |
| B. | Methionine |
| C. | N-formyl methionine |
| D. | A lanine |
| Answer» B. Methionine | |
| 9. |
A Codon is made up of |
| A. | Single nucleotide |
| B. | two nucleotides |
| C. | three nucleotides |
| D. | Four nucleotides |
| Answer» C. three nucleotides | |
| 10. |
Nucleus of a cell is the site of Synthesis of |
| A. | DNA |
| B. | m - RNA |
| C. | t - RNA |
| D. | All |
| Answer» D. All | |
| 11. |
DNA replication requires |
| A. | DNA polymerase only |
| B. | DNA polymerase and ligase |
| C. | Ligase only |
| D. | RNA polymerase |
| Answer» B. DNA polymerase and ligase | |
| 12. |
The enzyme involved in transcription is |
| A. | RNA polymerase |
| B. | DNA polymerase I |
| C. | DNA polymerase II |
| D. | DNA polymerase III |
| Answer» A. RNA polymerase | |
| 13. |
Enzymes needed for formation of repliction fork |
| A. | RNA polymerase and DNA polymerase I |
| B. | Helicase and gyrase |
| C. | Hexokinase and aldolase |
| D. | Ligase and endo nuclease |
| Answer» B. Helicase and gyrase | |
| 14. |
Okazaki fragments are Synthesized on |
| A. | Leading strands of DNA only |
| B. | Lagging Strands of DNA only |
| C. | Leading and LaggingStrands |
| D. | Complementary DNA Strand |
| Answer» B. Lagging Strands of DNA only | |
| 15. |
Which of the following is used in DNA multiplication? |
| A. | RNA polymerase |
| B. | DNA endonuclease |
| C. | DNA exonuclease |
| D. | DNA Polymerase |
| Answer» D. DNA Polymerase | |
| 16. |
t - RNA attaches aminoacid at its |
| A. | 31 end |
| B. | 51 end |
| C. | Anticodon |
| D. | Loop |
| Answer» A. 31 end | |
| 17. |
DNA acts as a template for synthesis of |
| A. | RNA |
| B. | DNA |
| C. | Both ‘a’ and ‘b’ |
| D. | Protein |
| Answer» C. Both ‘a’ and ‘b’ | |
| 18. |
Antiparallel strand in DNA is due to |
| A. | Disulphide linkage |
| B. | Hydorgen bond |
| C. | Phosphodiester bond |
| D. | Ionic bond |
| Answer» C. Phosphodiester bond | |
| 19. |
Multiplication of DNA is called |
| A. | Translation |
| B. | Replication |
| C. | Transduction |
| D. | Transcription |
| Answer» B. Replication | |
| 20. |
Which is the smallest RNA ? |
| A. | r RNA |
| B. | m RNA |
| C. | t - RNA |
| D. | nuclear RNA |
| Answer» C. t - RNA | |
| 21. |
Genetic information are transfered from nucleus to cytoplasm of cell through |
| A. | DNA |
| B. | RNA |
| C. | Lysosomes |
| D. | Anticodon |
| Answer» B. RNA | |
| 22. |
The information from RNA to DNA are transfered by which process |
| A. | Replication |
| B. | Transcription |
| C. | Translation |
| D. | Reverse transcription |
| Answer» D. Reverse transcription | |
| 23. |
Which statement is correct ?
|
| A. | A,B,C,D,E |
| B. | A, B, D |
| C. | A., C, D |
| D. | A, C, D, E |
| Answer» D. A, C, D, E | |
| 24. |
DNA molecule has uniform diameter due to ? |
| A. | Double stranded |
| B. | Presence of phosphate |
| C. | Specific base pairing between purine and pyrimidine |
| D. | Specific base pairing between purine and purine |
| Answer» C. Specific base pairing between purine and pyrimidine | |
| 25. |
In a transcription unit promotor is said to be located towards |
| A. | 31 end of structural gene |
| B. | 51 end of structural gene |
| C. | 51 end of template strand |
| D. | 31 end of template strand |
| Answer» D. 31 end of template strand | |
| 26. |
In DNA replication the primer is |
| A. | A Small deoxyribonucleotide polymer |
| B. | A small ribonucleotide polymer |
| C. | Helix destalilizing protein |
| D. | Enzyme taking part in joining nucleotides of new strands |
| Answer» B. A small ribonucleotide polymer | |
| 27. |
Non - sense codons take part in |
| A. | formation of unspecified aminoacids |
| B. | Terminating message of gene controlled protein synthesis |
| C. | Releasing t-RNA from polynucleotide chain |
| D. | Conversion of sense DNA in to non-sense one |
| Answer» B. Terminating message of gene controlled protein synthesis | |
| 28. |
select the correct sequence of following in DNA replication |
| A. | single stranded binding proteins - Helicase - Topoisomerase - DNA polymerase |
| B. | Helicase - single stranded binding proteins -Topoisomerase - DNA polymerase |
| C. | Helicase - DNA polymerase - Topoisomerase - Single stranded binding proteins |
| D. | Helicase - Topoisomerase - DNA polymerase - Single stranded binding proteins |
| Answer» B. Helicase - single stranded binding proteins -Topoisomerase - DNA polymerase | |
| 29. |
Which of the following enzymes can detect and correct the wrong inserted base during DNA replication ? |
| A. | DNA polymerase - I |
| B. | DNA polymerase - II |
| C. | Primase |
| D. | Ligase |
| Answer» A. DNA polymerase - I | |
| 30. |
Which one is a ribozyme ? |
| A. | Helicase |
| B. | Ribonuclease - P |
| C. | Peptidyl transferase |
| D. | Both (B) & (C) |
| Answer» D. Both (B) & (C) | |
| 31. |
Which of the following pairs is not correctly matched ? |
| A. | Recombinant DNA - DNA forming by union of segments of DNA from diffrent Sources |
| B. | Purines - Nitrogenous bases Cytosine , thymine and Uracil |
| C. | ATP - The principal energy carrying compound inthe cell |
| D. | r-RNA - RNA molecules found in ribosomes |
| Answer» B. Purines - Nitrogenous bases Cytosine , thymine and Uracil | |
| 32. |
Which one of the following pairs is correctly matched ? |
| A. | Ribosomal RNA - Carries amino acids to the site of protein synthesis |
| B. | Transcription - Process by which protein in synthesized |
| C. | Translation - Process by which m RNA carries the information from nucleus to ribosomes |
| D. | Anticodon - Site of t-RNA that binds to the m-RNA |
| Answer» D. Anticodon - Site of t-RNA that binds to the m-RNA | |
| 33. |
Which is not the step of translation ? |
| A. | Initiation |
| B. | Replication |
| C. | Elongation |
| D. | Termination |
| Answer» B. Replication | |
| 34. |
The enzyme amino acyl t-RNA-synthetase facilitates. |
| A. | Joining two neighbouring amino acids on ribosomes |
| B. | A doption of amino acids by a t-RNA molecule |
| C. | Insertion of amino acyl t-RNA into the ribosome sites |
| D. | Transfer of amino acyl t-RNA from the ribosomal ‘A’ site to ‘P’ site |
| Answer» B. A doption of amino acids by a t-RNA molecule | |
| 35. |
state the anticodon of initiation codon of protein synthesis |
| A. | UAC |
| B. | UUU |
| C. | CAU |
| D. | AUG |
| Answer» A. UAC | |
| 36. |
Which is the energy source for the process of elongation ? |
| A. | ATP |
| B. | GTP |
| C. | Creatine-PO4 |
| D. | All the above |
| Answer» B. GTP | |
| 37. |
What does a gene consist of ? |
| A. | Promoter |
| B. | Initiation site & termination site |
| C. | coding sequence |
| D. | All the above |
| Answer» D. All the above | |
| 38. |
Name the enzymes needed for lactose Catabolism in E.coli ? |
| A. | β - galactosidase, permease transacetylase |
| B. | β - galactosidasee Lactase, transacetylase |
| C. | β - galactosidase, lactase, permease |
| D. | Lactase, permease, transacetylase |
| Answer» A. β - galactosidase, permease transacetylase | |
| 39. |
What does operon contain ? |
| A. | Regulator gene + promotor gene |
| B. | Operator gene + structural gene |
| C. | Regulator gene + promotor gene structural gene |
| D. | Regulator gene + promotor gene + operator gene + structural gene |
| Answer» D. Regulator gene + promotor gene + operator gene + structural gene | |
| 40. |
Select correct match with respect to lac-operon model ? |
| A. | Active represser + inducer Inactive repressor |
| B. | Active repressor + corepressor Inactive repressor |
| C. | Inactive repressor + inducer Active repressor |
| D. | Inactive repressor + corepressor Active repressor |
| Answer» A. Active represser + inducer Inactive repressor | |
| 41. |
In relation of lac operon in E-coli , Which protein is not regulated by the repressor ? |
| A. | Tryptophan |
| B. | galactosidase |
| C. | Lactose permease |
| D. | Transacetylase |
| Answer» A. Tryptophan | |
| 42. |
Which is not correct regarding the activity of helicase during DNA replication ? |
| A. | Cuts hydrogen bomds |
| B. | Requires ATP |
| C. | separates DNA strands |
| D. | Stabilizes single strands |
| Answer» C. separates DNA strands | |
| 43. |
Which of the following enzyme is not produced by E. coli during lactose catabolism ? |
| A. | β - galactosidase |
| B. | Thioglactoside translacetylase |
| C. | Lactose dehydrogenase |
| D. | Lactose permease |
| Answer» C. Lactose dehydrogenase | |
| 44. |
Which is the incorrect statement regarding HGP ? |
| A. | HGP is an Indian scientific research project |
| B. | In 1990, the Project was initiated |
| C. | A working draft of the genome was announced in 2000 |
| D. | In February 2001, the analysis of the working draft was published |
| Answer» A. HGP is an Indian scientific research project | |
| 45. |
Humans have approximately _____ times more genes than E.coli |
| A. | 8 |
| B. | 15 |
| C. | 100 |
| D. | 50 |
| Answer» D. 50 | |
| 46. |
Which of the following is not according to the chargoff’s rule ? |
| A. | A = T |
| B. | C = G |
| C. | A + G = T + C |
| D. | A + T / G + C =1 |
| Answer» D. A + T / G + C =1 | |
| 47. |
Select the correct answer / answers from the following
|
| A. | 1, 2, 3 and 4, are corrent |
| B. | 1 and 2 are correct, 3 and 4 are false |
| C. | 1 and 3 are correct, 2 and 4 false |
| D. | 1, 2, 3 are correct, 4 is false |
| Answer» C. 1 and 3 are correct, 2 and 4 false | |
| 48. |
DNA replication in eukaryotes is |
| A. | Unidirectional with many origin |
| B. | Bidirectional with many origin |
| C. | Unidirectional with single origin |
| D. | Bidirectional with single origin |
| Answer» B. Bidirectional with many origin | |
| 49. |
Aminoacids lysine, serine and arginine are coded by how many codons ? |
| A. | 6, 4, and 3 respectively |
| B. | 4, 2 and 2 respectively |
| C. | 6 codons |
| D. | 4 codons |
| Answer» C. 6 codons | |
| 50. |
Which of the following amino acid is coded by 3 codons ? |
| A. | serine |
| B. | Proline |
| C. | Tryptophan |
| D. | Isoleucine |
| Answer» D. Isoleucine | |
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